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Regdanvimab for COVID-19 effective against Delta variant
The neutralizing antibody regdanvimab appears to be useful in the treatment of mild-to-moderate COVID-19, with a recent study showing that the drug may prevent disease worsening in patients, including those infected with the Delta variant.
Lower plasma ACE2 levels may partially mediate COVID-19 risks in overweight/obesity or low socioeconomic position
Lower plasma angiotensin-converting enzyme 2 (ACE2) levels may partially mediate COVID-19 risks in individuals with overweight/obesity or low socioeconomic position (SEP; referring to low educational attainment), according to a large-scale Mendelian randomization study conducted by researchers at the University of Hong Kong (HKU) and the Chinese University of Hong Kong (CUHK).
Cardiovascular death among seniors with pneumonia down with antibiotic therapy
In the treatment of older patients hospitalized with community-acquired pneumonia, the use of guideline-concordant antibiotic therapy significantly lowers the risk of cardiovascular death in the first year of follow-up, as reported in a study.
Oseltamivir as good as peramivir in influenza B but yields better outcomes in influenza A
Oseltamivir appears to have similar efficacy as peramivir in the treatment of young children with severe influenza B, a study has found. However, oseltamivir treatment leads to better recovery and shorter hospitalization in children with severe influenza A.
Investigational antisense oligonucleotide for chronic HBV infection shows positive results
Treatment with the antisense oligonucleotide bepirovirsen appears to lead to sustained loss of hepatitis B surface antigen (HBsAg) and hepatitis B virus (HBV) DNA in up to 10 percent of patients with chronic HBV infection, according to the results of the phase IIb study B-Clear.