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Aficamten outperforms metoprolol in obstructive HCM

11 Oct 2025 by

Two phase III trials presented at ESC 2025 have provided new insights into the role of myosin inhibitors in hypertrophic cardiomyopathy (HCM), with one trial demonstrating superiority over standard care in obstructive HCM and another failing to meet its primary endpoints in nonobstructive HCM.

Aficamten outperforms metoprolol in obstructive HCM

11 Oct 2025

Magnesium confers BP-lowering benefits in people with hypertension, hypomagnesemia

11 Oct 2025

Magnesium supplementation appears to substantially reduce blood pressure (BP) levels in individuals with hypertension and hypomagnesemia, especially those on antihypertensive medication, according to a systematic review and meta-analysis.

Magnesium confers BP-lowering benefits in people with hypertension, hypomagnesemia

11 Oct 2025

Does anticoagulant use improve survival in PAH?

09 Oct 2025

The use of anticoagulant therapy offers no survival benefit in patients with pulmonary arterial hypertension (PAH), a recent study has shown.

Does anticoagulant use improve survival in PAH?

09 Oct 2025

Elevated serum uric acid tied to high-risk coronary artery plaques

09 Oct 2025

Individuals with increased serum uric acid have a higher likelihood of showing high-risk coronary artery plaques on coronary CT angiography (CCTA), as reported in a retrospective study.

Elevated serum uric acid tied to high-risk coronary artery plaques

09 Oct 2025

PPIs unlikely linked to increased stroke risk in patients taking antithrombotics

09 Oct 2025 by

Researchers at the University of Hong Kong (HKU) have found that the risk of ischaemic stroke is not increased in patients on proton-pump inhibitor (PPI) monotherapy, but is increased in those coprescribed with antithrombotic drugs, possibly due to their underlying higher risk profiles.

PPIs unlikely linked to increased stroke risk in patients taking antithrombotics

09 Oct 2025

Engaging in physical activity may prevent MACE, death in people with T2D

08 Oct 2025 by

An inverse association exists between self-reported physical activity (PA) and the risk of major adverse cardiac events (MACE) and all-cause mortality among individuals with type 2 diabetes (T2D) and no previous cardiovascular disease (CVD), suggests a study presented at EASD 2025.

Engaging in physical activity may prevent MACE, death in people with T2D

08 Oct 2025

Stroke-heart syndrome associated with increased risk of incident dementia

08 Oct 2025 by

Patients with stroke-heart syndrome (SHS) may have increased risk of dementia in the early phase after a stroke, but this risk can be lowered to a level similar to those without SHS if adherent care is given, researchers from the University of Hong Kong (HKU) and their international collaborators have found.

Stroke-heart syndrome associated with increased risk of incident dementia

08 Oct 2025

CBT for insomnia improves sleep outcomes in patients with chronic disease

07 Oct 2025 by

Cognitive behavioural therapy (CBT) for insomnia (CBT-I) helps reduce its severity and improve other sleep outcomes in patients with chronic disease, such as chronic pain, cardiovascular disease, and cancer, according to the results of a meta-analysis.

CBT for insomnia improves sleep outcomes in patients with chronic disease

07 Oct 2025

Oxidative balance score inversely linked to advanced CKM risk

07 Oct 2025

Higher levels of oxidative balance score (OBS) are associated with a lower risk of advanced cardiovascular‒kidney‒metabolic (CKM) syndrome, reveals a study.

Oxidative balance score inversely linked to advanced CKM risk

07 Oct 2025

Boosting potassium wards off ventricular arrhythmias in patients with ICD

07 Oct 2025 by

Increasing low potassium levels improves clinical outcomes in patients with cardiovascular disease (CVD) and a high risk for ventricular arrhythmias, as shown in the POTCAST trial presented at ESC 2025.

Boosting potassium wards off ventricular arrhythmias in patients with ICD

07 Oct 2025

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Aficamten outperforms metoprolol in obstructive HCM

Aficamten outperforms metoprolol in obstructive HCM

Magnesium confers BP-lowering benefits in people with hypertension, hypomagnesemia

Magnesium confers BP-lowering benefits in people with hypertension, hypomagnesemia

Does anticoagulant use improve survival in PAH?

Does anticoagulant use improve survival in PAH?

Elevated serum uric acid tied to high-risk coronary artery plaques

Elevated serum uric acid tied to high-risk coronary artery plaques

PPIs unlikely linked to increased stroke risk in patients taking antithrombotics

PPIs unlikely linked to increased stroke risk in patients taking antithrombotics

Engaging in physical activity may prevent MACE, death in people with T2D

Engaging in physical activity may prevent MACE, death in people with T2D

Stroke-heart syndrome associated with increased risk of incident dementia

Stroke-heart syndrome associated with increased risk of incident dementia

CBT for insomnia improves sleep outcomes in patients with chronic disease

CBT for insomnia improves sleep outcomes in patients with chronic disease

Oxidative balance score inversely linked to advanced CKM risk

Oxidative balance score inversely linked to advanced CKM risk

Boosting potassium wards off ventricular arrhythmias in patients with ICD

Boosting potassium wards off ventricular arrhythmias in patients with ICD