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1 week off methotrexate works okay for RA patients receiving flu shot
Temporarily discontinuing methotrexate treatment for 1 week appears to induce satisfactory response to a seasonal influenza vaccine in patients with rheumatoid arthritis (RA), with a similar effect as a 2-week interruption schedule, according to a study.

Coronavirus surrogates may stay on meat, fish in cold storage for up to a month
Surrogates of SARS-CoV-2* – a lipid enveloped RNA bacteriophage (Phi6) and two animal coronaviruses (CoVs; MHV and TGEV**) – survived in cold-storage temperatures for 30 days, a study finds, highlighting the risk of viral survival on food products and potential transmission on humans upon consumption.

Gastric disease prevalence peaks during middle age, late adulthood
There appears to be a twin-peak prevalence profile (TPP) for diseases of the stomach, including Helicobacter pylori (Hp) infection, gastric cancer (GC), gastric intraepithelial neoplasia (GIN), and gastritis, according to a recent China study. The first peak typically occurs during middle-adulthood while the second peak happens in late life.

Negative attitude towards MSM living with HIV tied to low knowledge, worry about HIV
Ignorance and fear of HIV both contribute significantly to the negative attitudes towards men who have sex with men (MSM) living with the virus, suggests a study presented at the 24th International AIDS Conference (AIDS 2022) in Montreal, Canada.

Long-acting injectable HIV drug works for all ages
The long-acting combination of cabotegravir plus rilpivirine, administered as monthly or once-every-2-months jabs, appears to be effective in both older and younger patients living with HIV, with most maintaining virologic suppression through week 96, according to pooled data from the phase III ATLAS, FLAIR, and ATLAS-2M studies.

Tenofovir in mothers plus HBIG in infants best prevent vertical HBV transmission
For mothers with hepatitis B virus (HBV) infection who are positive for both hepatitis B surface and envelope antigens, administering a combination of hepatitis B vaccine and immunoglobulin (HBIG) in their infants plus tenofovir disoproxil fumarate (TDF) in the mothers themselves appears to be the best approach for preventing vertical disease transmission, according to a study.



