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Outpatient management of jaundice needed to lessen paediatric ED visits
Neonatal jaundice (NNJ) and pyrexia (NNP) are the most common diagnoses in the paediatric emergency department (PED) and during discharge from the hospital, a Singapore study has observed. In addition, the rates of hospital admission and referral from polyclinics and other clinics are higher than those in other series, driven by different healthcare structure, protocols, and workflows in the different studies.

SCLC: Hippocampal avoidance in prophylactic cranial irradiation a potential SoC
In patients with small-cell lung cancer (SCLC), hippocampal avoidance-prophylactic cranial irradiation (HA-PCI) better preserves cognitive function and has no adverse impact on the incidence of brain metastases, overall survival (OS) and quality of life (QoL) compared with standard PCI, a phase III randomized controlled trial has shown.

Add-on brivaracetam for epilepsy makes good in real-world practice
Long-term postmarketing data for adjunctive brivaracetam show that its use helps improve seizure control in patients with various epilepsy syndromes, even in those with prior exposure to levetiracetam. However, psychobehavioural adverse events (AEs) occur in one out of ten patients.

Omission of parametrial boost does not compromise local control, survival in modern era
Leaving out the use of external beam parametrial boost (EBPB) for locally advanced cervical cancer does not seem to negatively affect local control or survival in the era of image-guided brachytherapy, results of a study have shown. This then supports a reduced need for standardized use of parametrial boost.





