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Use of RAS inhibitors associated with lower cancer risk in T2D
A real-world study of over 250,000 type 2 diabetes (T2D) patients from Hong Kong has found that use of renin-angiotensin-system inhibitors (RASIs) is independently associated with reduced risk of cancer, including diabetes-related cancers and cancer-specific mortality in diabetes.

SGLT2 inhibitors potentially protective against dry eye disease
Type 2 diabetes (T2D) patients on sodium-glucose cotransporter 2 (SGLT2) inhibitors appear to be at lower risk of dry eye disease (DED) compared with their counterparts who are receiving glucagonlike peptide-1 receptor agonists (GLP-1 RAs), as shown in a study.

Lifestyle change lowers T2D risk in women with gestational diabetes mellitus history
Each additional optimal modifiable factor among women with a history of gestational diabetes mellitus (GDM) significantly contributes to a reduction in type 2 diabetes (T2D) risk, suggests a recent study. These associations are also present among individuals who are overweight/obese or are at greater genetic susceptibility to T2D.

Elobixibat affords metabolic benefits in type 2 diabetes
In type 2 diabetes (T2D) patients with constipation, treatment with elobixibat alleviates constipation while improving glucose metabolism and lowering serum low-density lipoprotein cholesterol (LDL-C) and arachidonic acid (AA) levels, according to the results of a single-arm pilot study.

Evolocumab safety, efficacy affirmed in Arabic patients
PCSK9 inhibition with evolocumab produces clinically meaningful and sustained reductions in certain lipid parameters in a predominantly Arabic population of individuals with familial hypercholesterolaemia (FH) and other non-FH indications, according to a study.



