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Clinicians vary as to how they manage drug–drug interactions (DDIs) with direct oral anticoagulants (DOACs) in clinical practice, with potentially substantial DDIs with DOACs still occurring despite computerized alerts, according to a study.
A bidirectional association exists between alopecia areata (AA) and major depressive disorder (MDD) among probands and unaffected siblings, reveals a study. This suggests that shared familial mechanisms tend to cause AA and MDD.
The addition of the anti-PD-1* monoclonal antibody pembrolizumab to platinum-based neoadjuvant chemotherapy (CT) led to a significant increase in the proportion of women with early triple-negative breast cancer (TNBC) who had a pathological complete response (pCR), the phase III KEYNOTE-522 trial has shown.
In healthy eyes, a thicker macula and ganglion cell-inner plexiform layer (GCIPL) is associated with better visual functioning, according to a recent Singapore study.
Antidepressants, particularly selective serotonin reuptake inhibitors (SSRIs), appear to increase the risk of fractures in older adults, a recent study has shown.
Adding liraglutide to first-line lifestyle therapy led to a significantly reduced BMI standard-deviation score (BMI SDS*) among obese adolescents who failed to respond to lifestyle therapy alone, according to a study presented at ENDO 2020.
