News &amp; Updates

Sotagliflozin shortens hospital stay, improves survival in T2D patients with worsening heart failure

Treatment with sotagliflozin in hospitalized patients with type 2 diabetes (T2D) leads to an increase in the number of days alive and out of the hospital (DAOH), a metric that may provide an additional patient-centred outcome to capture the totality of disease burden, reports a study.

Sotagliflozin shortens hospital stay, improves survival in T2D patients with worsening heart failure

P2Y12 inhibitor monotherapy noninferior to DAPT after coronary revascularization

05 Jul 2021 by

Treatment with P2Y12 inhibitor alone results in a comparable risk of death, stroke, or myocardial infarction (MI), as well as reduced risks of major bleeding, when compared with dual antiplatelet therapy (DAPT), according to a study. Such associations appear to be modified by sex and type of P2Y12 inhibitor, respectively.

P2Y12 inhibitor monotherapy noninferior to DAPT after coronary revascularization

Age-, sex-specific Asian references established for right heart function via CMR

05 Jul 2021 by

Cardiac magnetic resonance (CMR) can assess age- and sex-specific changes in right heart dimensions and function among Asians, helping doctors interpret disease states more accurately, according to a recent Singapore study.

Age-, sex-specific Asian references established for right heart function via CMR

Defining obesity with both BMI, WC leads to better long-term risk assessment after revascularization

Using the combination of body mass index (BMI) and waist circumference (WC) as measures of body composition seems to be a more appropriate indicator of the long-term risks obesity poses to patients with left-main coronary artery disease (LMCAD) or three-vessel disease (3VD) who have undergone coronary revascularization, a recent study has found.

Defining obesity with both BMI, WC leads to better long-term risk assessment after revascularization

Rise and fall in orthostatic BP tied to elevated PWV

An increase and a decrease in orthostatic blood pressure (BP) both correlate with greater pulse wave velocity (PWV), according to a study.

Rise and fall in orthostatic BP tied to elevated PWV

Antihypertensives do not impair survival in atezolizumab-treated cancer patients

Concomitant use of antihypertensive medications, including renin–angiotensin system inhibitor (RASi), does not appear to affect survival and immune-related safety outcomes during atezolizumab therapy in patients with solid cancers, results of a study have shown.

Antihypertensives do not impair survival in atezolizumab-treated cancer patients

Study discourages use of as-needed antihypertensives in hospitalized patients

Using as-needed blood pressure (BP)-lowering medication in hospitalized patients may do more harm than good, contributing to an abrupt drop in BP levels and heightened risks of ischaemic events, in-hospital mortality, and longer length of stay, according to a study.

Study discourages use of as-needed antihypertensives in hospitalized patients

Aerobic exercise reduces BP variability, central SBP in hypertensive people

Aerobic exercise leads to decreased blood pressure variability (BPV) and central systolic blood pressure (SBP) in hypertensive individuals, a study has found. On the other hand, isometric handgrip exercise does not lower BPV but tends to do so with central SBP.

Aerobic exercise reduces BP variability, central SBP in hypertensive people