News & Updates

Biologic DMARDs offer clinical benefits in adult-onset Still disease

15 May 2024 by

Use of biologic disease-modifying antirheumatic drugs (bDMARDs), particularly tocilizumab (TCZ), anakinra (ANK), and canakinumab (CNK), appears safe and effective in the treatment of adult-onset Still disease (AOSD), results of a systematic review and meta-analysis have shown.

Biologic DMARDs offer clinical benefits in adult-onset Still disease

15 May 2024

Perceptions of SLE flare differ between patients, physicians

15 May 2024

Patients differ from physicians regarding their views of systemic lupus erythematosus (SLE) flares, a study has found. The former see flares as days of having fatigue, pain, and skin issues, while the latter define flares as periods of elevated clinical SLE activity.

Perceptions of SLE flare differ between patients, physicians

15 May 2024

More frequent colonoscopy surveillance not needed for early-onset colorectal cancer

15 May 2024

Early-onset colorectal cancer (CRC) does not appear to carry an increased risk of advanced neoplasia compared with average-onset CRC and, hence, does not require more frequent colonoscopy surveillance, according to a study.

More frequent colonoscopy surveillance not needed for early-onset colorectal cancer

15 May 2024

Pregnancy complications raise long-term risk of type 2 diabetes

14 May 2024

Women who deliver preterm or have hypertensive disorders of pregnancy face increased long-term risk of type 2 diabetes, as shown in a retrospective study.

Pregnancy complications raise long-term risk of type 2 diabetes

14 May 2024

Sequential fosfomycin therapy beneficial in bacterial prostatitis caused by multidrug-resistant E coli

14 May 2024 by

Sequential treatment with the oral antibiotic fosfomycin appears to be safe and effective in the management of patients with acute bacterial prostatitis secondary to multidrug-resistant Escherichia coli, according to the phase IV FOS-PROST study.

Sequential fosfomycin therapy beneficial in bacterial prostatitis caused by multidrug-resistant E coli

14 May 2024

Changes in air pollutant concentrations up risk of small airway dysfunction

14 May 2024

The combined effect of annual changes in the concentrations of several air pollutants appear to elevate the risk of small airway dysfunction (SAD), suggests a study.

Changes in air pollutant concentrations up risk of small airway dysfunction

14 May 2024

Positive antibiotic interactions for MRSA bacteraemia tied to lower 14-day mortality

14 May 2024 by

Patients with positive in-vitro antibiotic interactions with vancomycin or daptomycin plus an antistaphylococcal β-lactam for methicillin-resistant Staphylococcus aureus (MRSA) bacteraemia appear to have greater survival at 2 weeks, as shown in a post hoc analysis of the CAMERA-2* study.

Positive antibiotic interactions for MRSA bacteraemia tied to lower 14-day mortality

14 May 2024

Uniform threshold to rule out MI works well in male, female patients

14 May 2024

A uniform cardiac troponin threshold to identify myocardial infarction (MI) risk demonstrates safety and efficacy in both male and female patients, reports a study.

Uniform threshold to rule out MI works well in male, female patients

14 May 2024

Inappropriate pneumonia diagnosis common, potentially harmful for hospitalized older adults

14 May 2024

The frequency of inappropriate diagnosis of community acquired pneumonia (CAP) is relatively high among hospitalized adults, especially those who are older, have dementia, or present with altered mental status, according to a study. In such cases, a full-course antibiotic treatment may be detrimental.

Inappropriate pneumonia diagnosis common, potentially harmful for hospitalized older adults

14 May 2024

Postoperative antibiotics do little to improve outcomes in paediatric gangrenous appendicitis

13 May 2024

In children who have nonperforated appendicitis with gangrenous, suppurative, and exudative (GSE) findings, the use of antibiotics following appendectomy does not lower the risk of surgical site infection (SSI), as shown in a study.

Postoperative antibiotics do little to improve outcomes in paediatric gangrenous appendicitis

13 May 2024

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Biologic DMARDs offer clinical benefits in adult-onset Still disease

Biologic DMARDs offer clinical benefits in adult-onset Still disease

Perceptions of SLE flare differ between patients, physicians

Perceptions of SLE flare differ between patients, physicians

More frequent colonoscopy surveillance not needed for early-onset colorectal cancer

More frequent colonoscopy surveillance not needed for early-onset colorectal cancer

Pregnancy complications raise long-term risk of type 2 diabetes

Pregnancy complications raise long-term risk of type 2 diabetes

Sequential fosfomycin therapy beneficial in bacterial prostatitis caused by multidrug-resistant E coli

Sequential fosfomycin therapy beneficial in bacterial prostatitis caused by multidrug-resistant E coli

Changes in air pollutant concentrations up risk of small airway dysfunction

Changes in air pollutant concentrations up risk of small airway dysfunction

Positive antibiotic interactions for MRSA bacteraemia tied to lower 14-day mortality

Positive antibiotic interactions for MRSA bacteraemia tied to lower 14-day mortality

Uniform threshold to rule out MI works well in male, female patients

Uniform threshold to rule out MI works well in male, female patients

Inappropriate pneumonia diagnosis common, potentially harmful for hospitalized older adults

Inappropriate pneumonia diagnosis common, potentially harmful for hospitalized older adults

Postoperative antibiotics do little to improve outcomes in paediatric gangrenous appendicitis

Postoperative antibiotics do little to improve outcomes in paediatric gangrenous appendicitis