News &amp; Updates

Breast cancer patients with urogenital atrophy may benefit from intravaginal laser therapy and hyaluronic acid suppositories, with a recent study showing that both help resolve related symptoms equally.

Intravaginal laser therapy, hyaluronic acid suppositories help counter urogenital atrophy

Metformin plus R-form verapamil improves glycaemic control in T2D

Combination therapy with metformin plus R-form verapamil (R-Vera) leads to significant improvements in glycaemic control by reducing haemoglobin A1c (HbA1c) and fasting plasma glucose (FPG) among patients with type 2 diabetes (T2D), reports a study.

Metformin plus R-form verapamil improves glycaemic control in T2D

19 Oct 2022

Lenvatinib-pembrolizumab combo fails to spring forward in HCC treatment

In the phase III LEAP*-002 study, a combination regimen comprising lenvatinib and pembrolizumab appeared to have similar efficacy and safety as lenvatinib monotherapy as first-line therapy for advanced hepatocellular carcinoma (HCC).

Lenvatinib-pembrolizumab combo fails to spring forward in HCC treatment

19 Oct 2022

Fenfluramine a promising long-term treatment option for Lennox-Gastaut syndrome

Treatment with fenfluramine produces sustained reductions in drop seizure frequency, especially generalized tonic-clonic seizures, in patients with Lennox-Gastaut syndrome (LGS), according to the results of an open-label extension trial.

Fenfluramine a promising long-term treatment option for Lennox-Gastaut syndrome

Rivaroxaban cuts radial artery occlusion rates

Rivaroxaban reduces radial artery occlusion rate, without significantly increasing bleeds, in patients undergoing transradial coronary procedures in the RIVARAD study.

Rivaroxaban cuts radial artery occlusion rates

Pitavastatin–ezetimibe combo affords large LDL-C reductions in dyslipidaemia

18 Oct 2022

Treatment with the combination of pitavastatin plus ezetimibe effectively lowers low-density lipoprotein cholesterol (LDL-C) levels by more than 50 percent, with a safety profile comparable to that of pitavastatin monotherapy, according to the results of a phase III study.

Pitavastatin–ezetimibe combo affords large LDL-C reductions in dyslipidaemia

18 Oct 2022

Alirocumab prior to PCI lowers LDL-C

18 Oct 2022 by

Starting alirocumab early in the hospital prior to undergoing percutaneous coronary intervention (PCI) reduces LDL-cholesterol (LDL-C) in STEMI* patients already on high-statin therapy.

Alirocumab prior to PCI lowers LDL-C

18 Oct 2022

Gabapentin offers pain relief during second-trimester surgical abortion

Preoperative administration of gabapentin helps reduce intraoperative pain in women undergoing second-trimester surgical abortion, leading to improved satisfaction with pain management, as shown in a randomized, controlled, double-blind trial.

Gabapentin offers pain relief during second-trimester surgical abortion

Low-dose trimethoprim-sulfamethoxazole safe, effective against PJP after kidney transplantation

Prophylactic treatment with trimethoprim (TMP)-sulfamethoxazole (SMX) at a low dose helps lower the risk of Pneumocystis jirovecii pneumonia (PJP) within 6 months following kidney transplantation, according to a study.

Low-dose trimethoprim-sulfamethoxazole safe, effective against PJP after kidney transplantation