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Chlorhexidine a safe, reasonable option for vaginal antisepsis
Vaginal antisepsis with chlorhexidine proves noninferior to that with iodine in terms of the incidence of gynaecologic surgery-associated urinary tract infection and vaginal irritation, as reported in a study.
Chlorhexidine a safe, reasonable option for vaginal antisepsis
06 Jul 2022PARG inhibition slows HCC progression, boosts efficacy of immune checkpoint therapy
In hepatocellular carcinoma (HCC), poly(ADP-ribose) glycohydrolase (PARG) may serve as an oncogene by modulating PARG/DDB1/c-Myc signaling and be used as a biomarker to identify HCC patients who may derive benefit from anti-PD-1 treatment, suggests a study.
PARG inhibition slows HCC progression, boosts efficacy of immune checkpoint therapy
05 Jul 2022Concurrent DOAC, tamoxifen use poses no elevated bleeding risk
In breast cancer patients receiving direct oral anticoagulants (DOACs), tamoxifen is safe to use and does not increase the risk of haemorrhage as compared with concurrent use of an aromatase inhibitor (AI), a study has found.
Concurrent DOAC, tamoxifen use poses no elevated bleeding risk
05 Jul 2022TNFi use carries only modest increase in psoriasis risk
The use of tumour necrosis factor-α inhibitor (TNFi) for inflammatory bowel disease (IBD) or rheumatoid arthritis (RA) raises the risk of developing psoriasis by twofold as compared with conventional therapy, although the absolute risk remains modest, as reported in a study.
TNFi use carries only modest increase in psoriasis risk
04 Jul 2022Statins reduce death, mechanical ventilation use in hospitalized COVID-19 patients
Hospitalized patients with COVID-19 who are treated with statins are less likely to undergo invasive mechanical ventilation or die, according to the results of a multicentre study in the US.