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Do bDMARDs prevent osteoporotic fractures in RA patients?
Use of biological disease-modifying antirheumatic drugs (bDMARDs) appears to have no benefit in the prevention of osteoporotic fractures among patients with rheumatoid arthritis (RA), according to the results of a recent study.
Do bDMARDs prevent osteoporotic fractures in RA patients?
01 Jul 2022Ultra-high-dose methylcobalamin may reduce clinical progression in early-stage ALS
Ultra-high-dose methylcobalamin (MeCbl) slowed functional decline in individuals with early-stage amyotrophic lateral sclerosis (ALS) with moderate progression, the JETALS* study has shown.
Ultra-high-dose methylcobalamin may reduce clinical progression in early-stage ALS
01 Jul 2022Novel PPARγ modulator shows therapeutic potential in acne vulgaris
In the treatment of patients with acne vulgaris, the investigational peroxisome proliferator-activated receptor-γ (PPARγ) modulator N-acetyl-GED-0507-34-LEVO (NAC-GED) 5% gel appears to help clear lesions and improve acne severity while being safe, according to the results of a phase IIb study.
Novel PPARγ modulator shows therapeutic potential in acne vulgaris
01 Jul 2022Ibrutinib-bendamustine-rituximab combo promising for older patients with mantle-cell lymphoma
A treatment combination comprising the Bruton’s tyrosine kinase (BTK) inhibitor ibrutinib plus bendamustine and rituximab, followed by rituximab maintenance therapy, improved progression-free survival (PFS) in older patients with untreated mantle-cell lymphoma, according to results of the SHINE* trial presented at ASCO 2022.
Ibrutinib-bendamustine-rituximab combo promising for older patients with mantle-cell lymphoma
30 Jun 2022Persistent ALT elevation triples risk of future T2D among overweight, obese children
Children with overweight or obesity risk developing future type 2 diabetes (T2D) by threefold in the presence of persistent elevations in alanine aminotransferases (ALT), according to a study presented at the 54th Annual Meeting of the European Society for Paediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN 2022).
Persistent ALT elevation triples risk of future T2D among overweight, obese children
30 Jun 2022Antioxidant cocktail works against diabetic polyneuropathy in T2D
Treatment with a combination of succinic acid, inosine, nicotinamide, and riboflavin (SINR) is safe and alleviates the symptoms of diabetic polyneuropathy in patients with type 2 diabetes (T2D), according to data from the CYLINDER study.