News &amp; Updates

More educational resources on oral cancer are needed, particularly aimed at community pharmacists, as shown in a UK study.

Further education on oral cancer necessary among community pharmacists

Nivolumab-AVD superior to brentuximab vedotin-AVD for advanced stage Hodgkin lymphoma

Treatment with nivolumab (N) plus doxorubicin, vinblastine, and dacarbazine (AVD) leads to improved progression-free survival (PFS) relative to brentuximab vedotin (BV) plus AVD in patients with advanced stage classic Hodgkin lymphoma (HL), according to the results of the SWOG S1826 study, which was presented at the recent ASCO 2023.

Nivolumab-AVD superior to brentuximab vedotin-AVD for advanced stage Hodgkin lymphoma

22 Jun 2023

GBDT model predicts IVIG-resistant Kawasaki disease

The gradient boosting decision tree (GBDT) model appears more reliable than previous models in predicting intravenous immunoglobulin (IVIG)-resistant Kawasaki disease (KD), reports a study.

GBDT model predicts IVIG-resistant Kawasaki disease

22 Jun 2023

Erdafitinib prevails in bladder cancer with select FGFRalt

The oral selective pan-FGFR tyrosine kinase inhibitor (TKI) erdafitinib demonstrated a survival advantage over chemotherapy, extending multiple efficacy endpoints in individuals with advanced or metastatic urothelial carcinoma (mUC) with FGFR alterations (FGFRalt) after previous anti-PD-(L)1 treatment, findings from the confirmatory phase III THOR trial have shown.

Erdafitinib prevails in bladder cancer with select FGFRalt

22 Jun 2023

Gliosis may explain depressive or cognitive symptoms after COVID

Patients with persistent depressive or cognitive symptoms after an acute SARS-CoV-2 infection have elevated gliosis – a secondary event to brain injury – and inflammation as shown in a case-control study.

Gliosis may explain depressive or cognitive symptoms after COVID

Pregnancy-associated cancers pose elevated mortality risk

Individuals diagnosed with cancer during pregnancy or postpartum appear to have increased overall 5-year mortality, although this is only true for specific cancer sites, according to a study.

Pregnancy-associated cancers pose elevated mortality risk

SGLT2 inhibitors score big, this time in gout

Patients initiated on gliflozins or flozins – also called sodium-glucose co-transporter 2 (SGLT2) inhibitors – for type 2 diabetes (T2D) who were previously on metformin had reductions in the incidents of gout of up to 60 percent compared with other second-line agents in a recent study.

SGLT2 inhibitors score big, this time in gout

22 Jun 2023

Vasomotor symptoms precede weight gain in women

Frequent vasomotor symptoms (VMS) appear to be associated with subsequent weight gain in middle-aged women, according to a study.

Vasomotor symptoms precede weight gain in women

Does 25(OH)D serum level affect renal function?

Increased serum levels of 25-hydroxyvitamin D (25[OH]D) show a significant association with genetically predicted chronic kidney disease (CKD), increased blood urea nitrogen (BUN), and decreased estimated glomerular filtration rate (eGFR), reports a Europe study. However, 25(OH)D appears to have no causal effect on renal function.

Does 25(OH)D serum level affect renal function?