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Fibromyalgia symptoms weakly predict RA activity after treatment
Higher levels of fibromyalgia (FM) symptoms in patients with rheumatoid arthritis (RA) are slightly indicative of worse disease activity following treatment with a disease-modifying antirheumatic drug (DMARD), suggest the results a recent study.
Fibromyalgia symptoms weakly predict RA activity after treatment
24 May 2023CHIP predicts adverse outcomes in atherosclerotic CVD
Clonal haematopoiesis of indeterminate potential (CHIP) appears to independently contribute to adverse outcomes in individuals with established atherosclerotic cardiovascular disease (ASCVD), reveals a recent study, noting the high risks in TET2 and SF3B1/SRSF2/U2AF1 CHIP.
CHIP predicts adverse outcomes in atherosclerotic CVD
23 May 2023Higher vitamin D dose beneficial for paediatric obesity-related asthma
A 50,000-IU loading dose of oral vitamin D plus 8,000 IU daily is effective and safe for increasing serum 25(OH)D levels to ≥40 ng/mL in children and adolescents with asthma who were overweight or obese, as opposed to the standard of care (SoC) dose of 600 IU daily, according to findings from the VDORA1* trial.
Higher vitamin D dose beneficial for paediatric obesity-related asthma
23 May 2023Selective autotaxin inhibition shows promise in diffuse cutaneous systemic sclerosis
The selective autotaxin inhibitor ziritaxestat shows therapeutic potential in patients with early diffuse cutaneous systemic sclerosis, conferring greater reductions in modified Rodnan skin score compared with placebo and potentially reducing fibrosis, according to data from the phase IIa NOVESA study.