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Brigatinib a potential standard treatment alternative for treatment-naive ALK+ NSCLC
In patients with advanced anaplastic lymphoma kinase-positive non-small cell lung cancer (ALK+ NSCLC) who were ALK inhibitor-naïve, brigatinib showed superior efficacy and safety over crizotinib, according to the final results of the phase III ALTA-1L* trial presented at ELCC 2022.
Brigatinib a potential standard treatment alternative for treatment-naive ALK+ NSCLC
30 Apr 2022Secondary OPINION analysis boosts safety profile of maintenance olaparib for ovarian cancer
In women with platinum-sensitive relapsed ovarian cancer without a deleterious or suspected deleterious germline BRCA1/BRCA2 mutation (non-gBRCAm), maintenance olaparib was well tolerated, according to the secondary safety results from the phase IIIb OPINION study presented at SGO 2022.
Secondary OPINION analysis boosts safety profile of maintenance olaparib for ovarian cancer
29 Apr 2022Dapagliflozin most effective in frail patients with heart failure
Treatment with dapagliflozin results in improvements in all outcomes, regardless of frailty status, among patients with symptomatic heart failure (HF) with reduced ejection fraction, reports a study. However, “more frail” patients have larger absolute reductions.
Dapagliflozin most effective in frail patients with heart failure
28 Apr 2022Annual flu jab in HF patients may lower hospitalization, pneumonia risk
An annual influenza vaccination does not lower the risk of cardiovascular (CV) outcomes in patients with heart failure (HF), though it may reduce the risk of pneumonia and hospitalization, according to results of the IVVE study presented at ACC.22.