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NSAID use ups risk of heart failure in T2DM patients
Use of nonsteroidal anti-inflammatory drugs (NSAIDs) tends to elevate the risk of first-time hospitalization for heart failure (HF) in patients with type 2 diabetes mellitus (T2DM), a study has shown. In addition, those with advanced age, elevated haemoglobin (Hb) A1c levels, and new users are particularly at higher risk.
NSAID use ups risk of heart failure in T2DM patients
17 Apr 2023Investigational imaging agent holds promise for diagnosing renal cancer
In the pivotal phase III ZIRCON study, PET/CT imaging with 89Zr-DFO-girentuximab, an investigational imaging agent, demonstrated potential in the noninvasive identification of clear-cell renal cell carcinoma (ccRCC) in patients with indeterminate renal masses (IDRM).
Investigational imaging agent holds promise for diagnosing renal cancer
17 Apr 2023Add-on immunotherapy improves PFS in 1L advanced or recurrent endometrial cancer
Adding dostarlimab or pembrolizumab to standard first-line (1L) chemotherapy significantly improves progression-free survival (PFS) in patients with advanced or recurrent endometrial cancer, two phase III trials have shown.
Add-on immunotherapy improves PFS in 1L advanced or recurrent endometrial cancer
17 Apr 2023Idecabtagene vicleucel boosts PFS and responses vs standard regimens in triple class–exposed R/R MM
Idecabtagene vicleucel (ide-cel), a B-cell maturation antigen–directed chimeric antigen receptor (CAR) T-cell therapy, improves progression-free survival (PFS) and responses vs standard regimens in patients with triple class–exposed relapsed and refractory multiple myeloma (R/R MM), the phase III KarMMa-3 trial has shown.