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SLN status optimizes adjuvant therapy decision-making in clinical stage IIB/C melanoma
The performance of a prognostic model with sentinel lymph node (SLN) biopsy status in assessing patient risk for 5-year melanoma-specific death is superior to that of a model with primary tumour staging factors alone for threshold mortality rates ≥30 percent, a study has shown.
SLN status optimizes adjuvant therapy decision-making in clinical stage IIB/C melanoma
07 Apr 2023Frailty may portend cognitive decline
Initial frailty status appears to be a potential predictor of the occurrence of the composite of probable dementia and mild cognitive impairment, and this association is strengthened by intensive blood pressure control, as reported in a study.
Frailty may portend cognitive decline
06 Apr 2023Adapted digital cognitive behavioural therapy helps the sleepless get better night's sleep
A smartphone-based Chinese culture-adapted digital cognitive behavioural therapy for insomnia (DCBT-I) appears beneficial, producing improvements in the severity of insomnia as compared with sleep education, according to a study.
Adapted digital cognitive behavioural therapy helps the sleepless get better night's sleep
06 Apr 2023High marks for modified-release oral PDE4 inhibitor in moderate-to-severe psoriasis
The modified-release formulation of novel oral phosphodiesterase-4 (PDE4) inhibitor orismilast shows therapeutic potential in adults with moderate-to-severe psoriasis, with high rates of clinical response as compared with placebo, according to data from the phase IIb IASOS trial presented at AAD 2023.