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Updated monarchE results show improved treatment effects of abemaciclib for breast cancer
In the preplanned overall survival (OS) interim analysis of the monarchE study, the combination of abemaciclib and endocrine therapy (ET) continued to provide benefit for individuals with HR+, HER2–, node-positive, high-risk early breast cancer even after completion of therapy.
Updated monarchE results show improved treatment effects of abemaciclib for breast cancer
28 Dec 2022Coeliac disease tied to higher risk of juvenile idiopathic, rheumatoid arthritis
Young patients with coeliac disease (CD) tend to develop juvenile idiopathic arthritis (JIA) three times more often than does the general population, while adult CD patients appear to have rheumatoid arthritis (RA) nearly twice as often, reveals a study.
Coeliac disease tied to higher risk of juvenile idiopathic, rheumatoid arthritis
26 Dec 2022Sovateltide: A new option to improve neuro outcomes after cerebral ischaemic stroke?
The endothelin-B receptor agonist sovateltide appears to improve neurological outcomes in patients with acute cerebral ischaemic stroke (ACIS), according to a phase III trial presented at WSC 2022.
Sovateltide: A new option to improve neuro outcomes after cerebral ischaemic stroke?
26 Dec 2022Prasugrel tops ticagrelor for reducing risk of ischaemic events in ACS patients with prior MI
Prasugrel appears to better protect against the risk of ischaemic events in patients with acute coronary syndrome (ACS) and prior myocardial infarction (MI) as compared with ticagrelor, without a trade-off in bleeding, a study has found.
Prasugrel tops ticagrelor for reducing risk of ischaemic events in ACS patients with prior MI
24 Dec 2022Pemafibrate reduces triglycerides, but not CV events, in patients with T2D, hypertriglyceridemia
Despite reducing triglyceride levels, pemafibrate does not reduce the risk of cardiovascular (CV) events among patients with type 2 diabetes (T2D) and hypertriglyceridemia, according to results of the PROMINENT trial presented at AHA 2022.