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Updated monarchE results show improved treatment effects of abemaciclib for breast cancer
In the preplanned overall survival (OS) interim analysis of the monarchE study, the combination of abemaciclib and endocrine therapy (ET) continued to provide benefit for individuals with HR+, HER2–, node-positive, high-risk early breast cancer even after completion of therapy.
Updated monarchE results show improved treatment effects of abemaciclib for breast cancer
28 Dec 2022Female, male infertility: Adherence to anti-inflammatory diets may bring new babies
Anti-inflammatory dietary patterns, such as the Mediterranean diet, may improve the chances of conception among couples who struggle with infertility, according to a recent review.
Female, male infertility: Adherence to anti-inflammatory diets may bring new babies
21 Dec 2022EMERALD updates highlight therapeutic potential of elacestrant for ER+/HER2– mBC
In the updated analysis of the phase III EMERALD trial, the next-generation oral SERD* elacestrant continued to show favourable signals for the treatment of ER+/HER2– metastatic breast cancer (mBC).
EMERALD updates highlight therapeutic potential of elacestrant for ER+/HER2– mBC
20 Dec 2022Metformin may reduce COVID-19 severity in prediabetes, PCOS
Among patients with prediabetes or polycystic ovary syndrome (PCOS), the use of metformin appears to be associated with lower incidence of severe COVID-19, according to a study.
Metformin may reduce COVID-19 severity in prediabetes, PCOS
19 Dec 2022Maintenance olaparib confers survival benefit for HRD+ ovarian cancer patients
In the final overall survival (OS) analysis of the phase III PAOLA-1*/ENGOT-ov25 trial, the addition of olaparib to bevacizumab provided a survival benefit for women with newly diagnosed advanced ovarian cancer with HRD**-positive (HRD+) tumours.
Maintenance olaparib confers survival benefit for HRD+ ovarian cancer patients
19 Dec 2022Gestational diabetes mellitus predisposes women to prediabetes, T2DM
Among women with a history of gestational diabetes mellitus (GDM), the conversion to prediabetes or type 2 diabetes mellitus (T2DM) appears to be high, a recent study has found.