News & Updates

Does teen pregnancy foretell subsequent risk of premature death?

12 Apr 2024

Teenage pregnancy has been linked to an increased risk of premature mortality in early adulthood in a recent study.

Does teen pregnancy foretell subsequent risk of premature death?

12 Apr 2024

Niraparib maintenance yields favourable OS trend in patients with ovarian cancer

12 Apr 2024 by

Maintenance treatment with niraparib, a potent, highly selective PARP* inhibitor, provides a favourable overall survival (OS) trend compared with placebo in Chinese patients with platinum-sensitive recurrent ovarian cancer (PSROC), regardless of germline BRCA (gBRCA) mutation status, according to the ﬁnal analysis of the NORA trial presented at SGO 2024.

Niraparib maintenance yields favourable OS trend in patients with ovarian cancer

12 Apr 2024

Paclitaxel-coated devices may prevent death in endovascular revascularization

11 Apr 2024

Exposure to paclitaxel-coated devices (PCDs) does not appear to increase the risk of death among patients who are undergoing endovascular revascularization for lower limb peripheral artery disease, suggest the results of DETECT, a nationwide, retrospective cohort study. In contrast, exposure to PADs may even help lower the risk of mortality.

Paclitaxel-coated devices may prevent death in endovascular revascularization

11 Apr 2024

Antihypertensive drugs help prevent dementia in older adults

11 Apr 2024

Use of antihypertensive medications can help reduce the risk of dementia among older people in the general population, results of a study have shown. In addition, the same benefit extends to the very old and frail patients.

Antihypertensive drugs help prevent dementia in older adults

11 Apr 2024

Add-on injectable agent may alter hypertension treatment landscape

11 Apr 2024 by

Patients with inadequately controlled hypertension (HTN) may benefit from a single subcutaneous (SC) injection of the investigational RNAi therapeutic zilebesiran, on top of standard antihypertensives, findings from the phase II KARDIA-2 trial suggest.

Add-on injectable agent may alter hypertension treatment landscape

11 Apr 2024

Transient elastography scores accurately predict liver-related events in MASLD

11 Apr 2024 by

Vibration-controlled transient elastography (VCTE)–based Agile scores, developed for diagnosis of advanced fibrosis (Agile 3+ score) and cirrhosis (Agile 4 score) in patients with metabolic dysfunction–associated steatotic liver disease (MASLD), are highly accurate in predicting liver-related events (LREs) and may be suitable alternatives to liver biopsy in routine clinical practice and phase IIb/III clinical trials for steatohepatitis, researchers from the VCTE-Prognosis Study Group have reported.

Transient elastography scores accurately predict liver-related events in MASLD

11 Apr 2024

Daytime sleepiness: A hidden cause of behavioural and emotional issues in OSA children

11 Apr 2024 by

Excessive daytime sleepiness (EDS) is a risk factor for behavioural and emotional issues in children with obstructive sleep apnoea (OSA), researchers from the Chinese University of Hong Kong (CUHK) have shown.

Daytime sleepiness: A hidden cause of behavioural and emotional issues in OSA children

11 Apr 2024

Does the ACC pathway work for patients with chest pain?

10 Apr 2024

The expert consensus decision pathway recently published by the American College of Cardiology (ACC) has demonstrated its safety and efficacy in people with chest pain participating in an observational cohort study. However, those with coronary artery disease (CAD) may not benefit from such strategy.

Does the ACC pathway work for patients with chest pain?

10 Apr 2024

TriClip device gets FDA nod for leaky heart valve

10 Apr 2024 by

The US Food and Drug Administration (FDA) has approved the TriClip device for transcatheter edge-to-edge repair (TEER) in patients with severe tricuspid regurgitation (TR) or a leaky heart valve who are not eligible for surgery.

TriClip device gets FDA nod for leaky heart valve

10 Apr 2024

APOC3 inhibition shows therapeutic potential in severe hypertriglyceridemia

10 Apr 2024 by

Treatment with plozasiran, an experimental small interfering–RNA drug that targets apolipoprotein C3 (APOC3) gene, helps regulate triglyceride levels, bringing them below the critical threshold associated with acute pancreatitis for most patients with severe hypertriglyceridemia, according to the phase IIb SHASTA-2* study.

APOC3 inhibition shows therapeutic potential in severe hypertriglyceridemia

10 Apr 2024

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Does teen pregnancy foretell subsequent risk of premature death?

Does teen pregnancy foretell subsequent risk of premature death?

Niraparib maintenance yields favourable OS trend in patients with ovarian cancer

Niraparib maintenance yields favourable OS trend in patients with ovarian cancer

Paclitaxel-coated devices may prevent death in endovascular revascularization

Paclitaxel-coated devices may prevent death in endovascular revascularization

Antihypertensive drugs help prevent dementia in older adults

Antihypertensive drugs help prevent dementia in older adults

Add-on injectable agent may alter hypertension treatment landscape

Add-on injectable agent may alter hypertension treatment landscape

Transient elastography scores accurately predict liver-related events in MASLD

Transient elastography scores accurately predict liver-related events in MASLD

Daytime sleepiness: A hidden cause of behavioural and emotional issues in OSA children

Daytime sleepiness: A hidden cause of behavioural and emotional issues in OSA children

Does the ACC pathway work for patients with chest pain?

Does the ACC pathway work for patients with chest pain?

TriClip device gets FDA nod for leaky heart valve

TriClip device gets FDA nod for leaky heart valve

APOC3 inhibition shows therapeutic potential in severe hypertriglyceridemia

APOC3 inhibition shows therapeutic potential in severe hypertriglyceridemia