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DOACs, VKAs show similar efficacy, safety for VTE in octogenarians
In an international multi-database cohort study, direct oral anticoagulants (DOACs) demonstrated comparable efficacy and safety with vitamin K antagonists (VKAs) for octogenarians with venous thromboembolism (VTE).
DOACs, VKAs show similar efficacy, safety for VTE in octogenarians
01 Mar 2023Diet, physical activity help lower cardiometabolic disease risk
Behavioural weight-loss interventions, such as diet alone and diet plus physical activity (PA), induce a beneficial change in biomarkers of insulin resistance and cardiometabolic health in adults with overweight or obesity, reports a study. However, no additional benefit has been observed with the addition of moderate-intensity PA to a diet-only intervention.
Diet, physical activity help lower cardiometabolic disease risk
27 Feb 2023Adipose tissue–targeted nanoparticles may improve treatment of obesity and atherosclerosis
Researchers from the University of Hong Kong (HKU) have developed a nanoparticle-based targeted drug delivery system that selectively transports thyroid hormone (TH) to adipose tissue, which may improve treatment of obesity and its related cardiometabolic complications by overcoming serious adverse events (AEs) associated with systematic TH administration.
Adipose tissue–targeted nanoparticles may improve treatment of obesity and atherosclerosis
27 Feb 2023Tirofiban improves functional outcome, prevents haemorrhage in stroke patients
Endovascular treatment (EVT) with intravenous tirofiban prior to thrombectomy appears to improve functional outcome and reduce the risk of any intracranial haemorrhage in patients with large vessel occlusion treated within 4.5 hours after stroke onset compared with alteplase, a study has shown.
Tirofiban improves functional outcome, prevents haemorrhage in stroke patients
26 Feb 2023Depression prevalent in women after small vessel stroke
Patients with mild small vessel stroke (SVS) are nearly 7 times more likely to experience depression within 3 months of the incident stroke than those without a history of stroke, reveals a recent study.