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Synaptic variability lowers cortical gamma oscillation power in schizophrenia
Gamma oscillation power in the prefrontal cortex (PFC) in schizophrenia can significantly decrease with greater variability in excitatory synaptic strength across parvalbumin interneurons (PVIs), together with other modest synaptic alterations in these neurons, suggests a recent study.
Synaptic variability lowers cortical gamma oscillation power in schizophrenia
08 Apr 2022Risk of stroke lower with potent P2Y12 inhibitors vs clopidogrel in Chinese ACS patients
A retrospective study of over 6,000 Chinese patients with acute coronary syndrome (ACS) who underwent first-ever percutaneous coronary intervention (PCI) has shown that use of potent P2Y12 inhibitors, such as ticagrelor and prasugrel, is associated with lower risk of stroke than clopidogrel.
Risk of stroke lower with potent P2Y12 inhibitors vs clopidogrel in Chinese ACS patients
08 Apr 2022Add-on amantadine lessens “off” episodes in Parkinson’s disease
A delayed release/extended release (DR/ER) formulation of amantadine can help reduce breakthrough symptoms in Parkinson’s disease patients when the effect of levodopa therapy wears off, as shown in a recent study.