News &amp; Updates

Low serum iron (SI) and total iron binding capacity (TIBC) may lead to significantly worse Crohn’s disease (CR), reports a recent study.

Low serum iron, total iron binding capacity worsen Crohn’s disease

Sofosbuvir easy on the kidneys

Use of sofosbuvir-based direct-acting antiviral regimens for treating hepatitis C virus (HCV) in clinical trial participants with chronic kidney disease (CKD) does not appear to worsen estimated glomerular filtration rate levels, according to a study. Furthermore, the drug does not appear to contribute to an increased risk of end-stage renal disease among HCV patients with CKD treated in clinical practice.

Sofosbuvir easy on the kidneys

15 Mar 2022

Lenvatinib + pembrolizumab improves PFS in East Asian patients with advanced RCC

15 Mar 2022 by

Lenvatinib + pembrolizumab combination regimen improves progression-free survival (PFS) compared with sunitinib in a subset of East Asian patients with advanced renal cell carcinoma (aRCC), a finding that was similar to that of the global population of the CLEAR* trial, according to a subanalysis presented at ASCO GU 2022.

Lenvatinib + pembrolizumab improves PFS in East Asian patients with advanced RCC

Two-stage, one-stage surgeries safe, effective for paediatric CD

Two-stage and one-stage surgeries are comparably effective and safe in children with Crohn’s disease (CD), reports a recent case series.

Two-stage, one-stage surgeries safe, effective for paediatric CD

Family visitation during ICU stay matters a lot for critical illness survivors

Having an in-person family visit in the intensive care unit (ICU) makes a difference in the long-term mental health of patients, with a recent study suggesting that it lowers the risk of psychiatric disorders up to 1 year after hospital discharge.

Family visitation during ICU stay matters a lot for critical illness survivors

Female, non-White oncologists get lower satisfaction scores from patients

Asian and Hispanic oncologists, as well as female oncologists treating genitourinary malignancies, receive lower patient satisfaction scores (PSS), according to a study.

Female, non-White oncologists get lower satisfaction scores from patients

Polypharmacy in IBD interferes with treatment adherence, therapeutic success

Polypharmacy (PP) arises in nearly one in five patients with inflammatory bowel disease (IBD), particularly in older adults and those with comorbidity, according to a study, adding that PP can complicate adherence to treatment and therapeutic success.

Polypharmacy in IBD interferes with treatment adherence, therapeutic success

14 Mar 2022

Salvage chemotherapy better than surgery in patients with elevated tumour markers

Salvage chemotherapy is preferable over surgery in patients with alpha-fetoprotein (AFP) >30 µg/l and human chorionic gonadotropin (HCG) ≥20 mIU/ml after first-line chemotherapy, suggests a study.

Salvage chemotherapy better than surgery in patients with elevated tumour markers

L-arginine, tadalafil boost Li-ESWT effect for ED

In men with erectile dysfunction (ED), adjuvant daily oral therapy with L-arginine and tadalafil was effective and safe in enhancing the efficacy and duration of benefits of low-intensity extracorporeal shockwave therapy (Li-ESWT), a study has shown.

L-arginine, tadalafil boost Li-ESWT effect for ED

14 Mar 2022

People who trust formal information source more likely to get COVID-19 jab