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Add-on trilaciclib boosts antitumour effects of chemo combinations for triple-negative breast cancer
Pretreatment with the cyclin-dependent kinase 4/6 inhibitor trilaciclib appears to enhance the antitumour efficacy of gemcitabine plus carboplatin, with significant survival gains for patients with metastatic triple-negative breast cancer (mTNBC), according to the results of a phase II trial.
Add-on trilaciclib boosts antitumour effects of chemo combinations for triple-negative breast cancer
24 Feb 2022
Dysglycaemia may increase likelihood of deterioration in non-severe COVID-19 patients
Patients with non-severe coronavirus disease 2019 (COVID-19) who have worse glycaemic status are more likely to deteriorate clinically, but glycaemic status does not adversely impact neutralizing antibody (NAb) responses, researchers from the University of Hong Kong have shown.
Dysglycaemia may increase likelihood of deterioration in non-severe COVID-19 patients
24 Feb 2022
Tenecteplase still feasible up to 24 hours after a stroke
Intravenous thrombolysis with tenecteplase up to 24 hours after a stroke appears to re-establish blood flow in patients with large-vessel acute ischaemic stroke selected with advanced imaging, the phase IIa CHABLIS-T study has shown.
Tenecteplase still feasible up to 24 hours after a stroke
24 Feb 2022
Booster dose effective in reducing COVID-19 across ages in adults
The risk of COVID-19 is substantially reduced in adults who receive a third “booster” dose of the BNT162b2 vaccine regardless of their age, according to a study from Israel.
Booster dose effective in reducing COVID-19 across ages in adults
23 Feb 2022
Post-MPI statin use prevents MACE in patients with elevated coronary artery calcium score
Use of moderate- to high-intensity statins (MHIS) after myocardial perfusion imaging (MPI) leads to significantly fewer major adverse cardiovascular events (MACE) and is an independent negative predictor for 24-months MACE among patients with normal MPI and coronary artery calcium (CAC) score >300, a Singapore study has shown.
Post-MPI statin use prevents MACE in patients with elevated coronary artery calcium score
23 Feb 2022
Are patients with psoriatic arthritis at higher risk of death?
Patients with psoriatic arthritis (PsA) do not appear to be at increased risk of mortality from all causes, reveals a study. Moreover, the specific proportionate mortality rate (PMR) in this cohort is similar to that of the general population.