Olanzapine plus samidorphan tied to less weight gain in schizophrenia
Treatment with the combination of olanzapine and samidorphan results in significantly less weight gain and smaller increases in waist circumference compared with olanzapine alone, results of a phase III study have shown. In addition, the combination treatment is well tolerated, and its antipsychotic efficacy is comparable to that of olanzapine monotherapy.
