APOC3 inhibition shows therapeutic potential in severe hypertriglyceridemia
10 Apr 2024
byJairia Dela Cruz
Treatment with plozasiran, an experimental small interfering–RNA drug that targets apolipoprotein C3 (APOC3) gene, helps regulate triglyceride levels, bringing them below the critical threshold associated with acute pancreatitis for most patients with severe hypertriglyceridemia, according to the phase IIb SHASTA-2* study.
