News &amp; Updates

Risk of death higher in people with vs without psoriasis

Individuals with psoriatic disease (PsD) are at greater risk of all-cause mortality than those without PsD, reveals a Taiwan study. Specifically, the risk of death is higher in patients with psoriasis but not in those with psoriatic arthritis (PsA).

Risk of death higher in people with vs without psoriasis

Chronic medical, psychiatric comorbidities common in paediatric hidradenitis suppurativa

Children with hidradenitis suppurativa (HS) are prone to a number of metabolic, endocrinologic, dermatologic, psychiatric, and genetic comorbidities, including obesity, anxiety, and acne vulgaris, according to the findings of a systematic review and meta-analysis.

Chronic medical, psychiatric comorbidities common in paediatric hidradenitis suppurativa

Bispecific antibody overcomes P. aeruginosa infection in patients with bronchiectasis

The bispecific antibody gremubamab, which targets two proteins on the surface of Pseudomonas aeruginosa, has been shown to substantially reduce bacterial load and improve quality of life for infected bronchiectasis patients in the phase II GREAT-2 study.

Bispecific antibody overcomes P. aeruginosa infection in patients with bronchiectasis

Is it safe to take abelacimab before a procedure?

Patients with atrial fibrillation (AF) who have been treated with the long-acting factor XI inhibitor abelacimab may undergo invasive procedures, as shown by the low rates of bleeding in a recent study.

Is it safe to take abelacimab before a procedure?

Analogue bests human insulin in T2D patients with kidney failure

Analogue insulin demonstrates superiority over human insulin in terms of survival among patients with kidney failure and type 2 diabetes (T2D) who are receiving peritoneal dialysis, according to a study presented at ERA 2025.

Analogue bests human insulin in T2D patients with kidney failure

20 Jun 2025

Degenerative disc disease in PsA patients tied to old age, back pain, male sex

Young patients with psoriatic arthritis (PsA) are predisposed to degenerative disc disease (DDD), which appears to be associated with demographic features, comorbidities, and disease-related factors, suggests a recent study.

Degenerative disc disease in PsA patients tied to old age, back pain, male sex

CONFIDENCE supports simultaneous MR, SGLT2 inhibition in CKD and T2D

The phase II CONFIDENCE* trial shows the benefit of dual therapy with the selective ns-MRA** finerenone and the SGLT2i** empagliflozin vs either agent alone in individuals with chronic kidney disease (CKD) and type 2 diabetes (T2D).

CONFIDENCE supports simultaneous MR, SGLT2 inhibition in CKD and T2D

20 Jun 2025

Cabozantinib plus atezolizumab improves PFS in mCRPC after progression on ARPI

In the treatment of patients with metastatic castration-resistant prostate cancer (mCRPC) with extrapelvic soft-tissue metastases that has progressed on an androgen receptor pathway inhibitor (ARPI), the combination of cabozantinib plus atezolizumab appears to prolong progression-free survival (PFS), according to data from the open-label phase 3 CONTACT-02 trial.

Cabozantinib plus atezolizumab improves PFS in mCRPC after progression on ARPI

Long-term odevixibat shows sustained benefits in ALGS

Long-term treatment with odevixibat led to sustained improvements in pruritus scores and reductions in serum bile acid (sBA) levels among patients with Alagille syndrome (ALGS), based on a pooled analysis of the phase III ASSERT and ASSERT-EXT studies presented at ESPGHAN 2025.

Long-term odevixibat shows sustained benefits in ALGS