News &amp; Updates

Treatment with tenofovir alafenamide (TAF) is generally safe and effective for the prevention of hepatitis B virus (HBV) mother-to-child transmission (MTCT), reports a study, noting that the expected 8-week prenatal duration is feasible.

TAF prophylaxis prevents mother-to-child transmission of HBV

MIRASOL final analysis: MIRV remains superior to chemo for ovarian cancer

13 May 2025 by

In the final overall survival (OS) analysis of the phase III MIRASOL trial, the survival benefit previously reported with the antibody drug conjugate mirvetuximab soravtansine (MIRV) remains superior to investigator’s choice chemotherapy (ICC) for the treatment of folate receptor alpha-positive, platinum-resistant ovarian cancer (FRα+ PROC).

MIRASOL final analysis: MIRV remains superior to chemo for ovarian cancer

Intensive BP-lowering therapy safe for patients with acute ICH

Reducing systolic blood pressure (SBP) to a target of less than 140 mm Hg does not appear to have any negative effects on diffusion-weighted imaging lesion frequency and volume in patients with acute intracerebral haemorrhage (ICH), as shown in ICHADAPT-2*.

Intensive BP-lowering therapy safe for patients with acute ICH

Long-term use of antidepressants linked to sudden cardiac death

13 May 2025 by

New research presented at EHRA 2025 has shown that patients who have taken antidepressants for extended periods are at increased risk of sudden cardiac death.

Long-term use of antidepressants linked to sudden cardiac death

Nerve-sparing technique preserves erectile function after RARP

13 May 2025 by

A nerve-sparing technique decreases erectile dysfunction in men undergoing robot-assisted radical prostatectomy (RARP) for prostate cancer in a phase III study.

Nerve-sparing technique preserves erectile function after RARP

13 May 2025

Another win for semaglutide: Improved outcomes in MASH with fibrosis

12 May 2025 by

Semaglutide may also confer hepatoprotective benefits, with interim efficacy data from the ongoing phase III ESSENCE study showing that the glucagon-like peptide-1 (GLP-1) receptor agonist helps dial down disease activity in patients with metabolic dysfunction–associated steatohepatitis (MASH) and moderate-to-severe fibrosis.

Another win for semaglutide: Improved outcomes in MASH with fibrosis

Intrinsic motivations for healthy lifestyle help reduce postpartum weight

12 May 2025 by

Greater intrinsic motivation for engaging in healthy lifestyle behaviours appears to promote long-term postpartum weight reduction and may be a promising target for interventions, suggests a study.

Intrinsic motivations for healthy lifestyle help reduce postpartum weight

Sleeping well before undergoing surgery tied to smoother recovery

Gynaecologic oncology patients with better sleep efficiency in the days before a surgical procedure are more likely to have fewer postoperative complications and require lower doses of opioid pain medication upon hospital discharge, according to a study.

Sleeping well before undergoing surgery tied to smoother recovery

Oral as good as extended-release injectable naltrexone for hospitalized adults with AUD

For hospitalized individuals initiating treatment for alcohol use disorder (AUD), oral naltrexone is equally efficacious as the extended-release injectable formulation in terms of reducing heavy drinking days, as shown in a study.

Oral as good as extended-release injectable naltrexone for hospitalized adults with AUD

Faricimab outclasses aflibercept in treatment of nAMD

In adult patients with treatment-naive neovascular age-related macular degeneration (nAMD), the use of faricimab shows superior anatomic outcome compared with aflibercept during the head-to-head dosing phase, reports a study.

Faricimab outclasses aflibercept in treatment of nAMD