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NIPS regimen improves OS in gastric cancer with peritoneal metastasis

12 Mar 2025 by

Among patients with gastric cancer and peritoneal metastasis, treatment with neoadjuvant intraperitoneal–systemic (NIPS) regimen, which consists of intraperitoneal (IP) and intravenous (IV) paclitaxel plus S-1, significantly improved overall survival (OS) compared with IV paclitaxel plus S-1 only (PS regimen), according to the DRAGON-01 trial presented at ASCO GI 2025.

NIPS regimen improves OS in gastric cancer with peritoneal metastasis

12 Mar 2025

HPV vaccines useful for managing actinic keratosis

11 Mar 2025

Standard α-HPV vaccination appears to reduce the burden of actinic keratosis (AK) in individuals with multiple lesions, according to the VAXAK trial.

HPV vaccines useful for managing actinic keratosis

11 Mar 2025

Xanomeline/trospium improves cognition in acute schizophrenia patients with impairment

11 Mar 2025

The use of xanomeline/trospium chloride brings significant cognitive improvements to acute schizophrenia patients with prespecified impairments compared with placebo, a study has shown.

Xanomeline/trospium improves cognition in acute schizophrenia patients with impairment

11 Mar 2025

Mobile app tracks BP changes in pregnant women

11 Mar 2025 by

Blood pressure (BP) estimates in pregnant women of the mobile app OptiBP meet the AAMI/ESH/ISO 81060-2:2018 criteria and are on a par with that of an oscillometric device, reports a study.

Mobile app tracks BP changes in pregnant women

11 Mar 2025

Ondansetron plus SRI eases OCD severity

11 Mar 2025

Treatment with high-dose ondansetron shows no effect on sensory phenomena (SP) in patients with obsessive-compulsive disorder (OCD), according to a study.

Ondansetron plus SRI eases OCD severity

11 Mar 2025

Treatment de-escalation safe in patients with ERBB2-positive early breast cancer and high TILs

11 Mar 2025 by

De-escalation of chemotherapy dose and trastuzumab duration may not increase the risk of distant relapse or death in patients with ERBB2-positive (also referred to as HER2-positive) early breast cancer and tumour infiltrating lymphocyte (TIL) levels of ≥20 percent, according to a 10-year analysis of the phase III ShortHER trial.

Treatment de-escalation safe in patients with ERBB2-positive early breast cancer and high TILs

11 Mar 2025

Replacing butter with plant-based oils good for longevity

11 Mar 2025

Switching from butter to plant-based oils such as olive, soybean, or canola may help prevent premature deaths, as reported in a study.

Replacing butter with plant-based oils good for longevity

11 Mar 2025

Radiotherapy plus short-course ADT confers survival benefit in oligometastatic prostate cancer

11 Mar 2025

In patients with oligometastatic hormone-sensitive prostate cancer, the combination of stereotactic body radiotherapy (SBRT) plus a short course of androgen deprivation therapy (ADT) appears to improve progression-free survival (PFS), according to the phase II RADIOSA trial.

Radiotherapy plus short-course ADT confers survival benefit in oligometastatic prostate cancer

11 Mar 2025

Efficacy benefit of nivolumab plus cabozantinib combo in aRCC continues through final results

11 Mar 2025 by

The long-term efficacy benefit of the nivolumab and cabozantinib combination vs sunitinib as a frontline treatment for aRCC is observed through the final results of CheckMate 9ER, with the report covering a minimum follow-up of 5 years first presented at ASCO GU 2025

Efficacy benefit of nivolumab plus cabozantinib combo in aRCC continues through final results

11 Mar 2025

Japanese adults with obesity lose weight with once-weekly tirzepatide

10 Mar 2025

Taking tirzepatide once a week appears to result in clinically meaningful reductions in body weight for Japanese adults with obesity, according to the results of the phase III multicentre SURMOUNT-J trial

Japanese adults with obesity lose weight with once-weekly tirzepatide

10 Mar 2025

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NIPS regimen improves OS in gastric cancer with peritoneal metastasis

NIPS regimen improves OS in gastric cancer with peritoneal metastasis

HPV vaccines useful for managing actinic keratosis

HPV vaccines useful for managing actinic keratosis

Xanomeline/trospium improves cognition in acute schizophrenia patients with impairment

Xanomeline/trospium improves cognition in acute schizophrenia patients with impairment

Mobile app tracks BP changes in pregnant women

Mobile app tracks BP changes in pregnant women

Ondansetron plus SRI eases OCD severity

Ondansetron plus SRI eases OCD severity

Treatment de-escalation safe in patients with ERBB2-positive early breast cancer and high TILs

Treatment de-escalation safe in patients with ERBB2-positive early breast cancer and high TILs

Replacing butter with plant-based oils good for longevity

Replacing butter with plant-based oils good for longevity

Radiotherapy plus short-course ADT confers survival benefit in oligometastatic prostate cancer

Radiotherapy plus short-course ADT confers survival benefit in oligometastatic prostate cancer

Efficacy benefit of nivolumab plus cabozantinib combo in aRCC continues through final results

Efficacy benefit of nivolumab plus cabozantinib combo in aRCC continues through final results

Japanese adults with obesity lose weight with once-weekly tirzepatide

Japanese adults with obesity lose weight with once-weekly tirzepatide