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Vaccines protect liver disease patients against severe COVID-19

20 Jan 2024 by

Patients with liver disease develop antibodies and T-cell responses following three shots of COVID-19 vaccines, while those who have been infected with SARS-CoV-2 develop mild symptoms only, reports a recent study.

Vaccines protect liver disease patients against severe COVID-19

20 Jan 2024

Shortened terlipressin therapy after endoscopic haemostasis as effective as 3-day course

20 Jan 2024

In cirrhosis patients with acute variceal bleeding (AVB), treatment with terlipressin for a single day yields similar rebleeding and mortality rates as 3-day treatment following endoscopic haemostasis, while having an overall superior safety profile, according to a study.

Shortened terlipressin therapy after endoscopic haemostasis as effective as 3-day course

20 Jan 2024

Linaclotide improves bowel movement frequency in children with functional constipation

20 Jan 2024 by

Once-daily treatment with linaclotide, a guanylate cyclase C agonist, significantly improved the frequency of spontaneous bowel movements (SBMs) in paediatric patients with functional constipation, according to a recent study.

Linaclotide improves bowel movement frequency in children with functional constipation

20 Jan 2024

Probiotic Bif195 helps protect against aspirin-induced stomach damage

19 Jan 2024 by

The probiotic strain Bifidobacterium breve (Bif195), when co-administered with aspirin, appears to mitigate stomach injury caused by aspirin, according to the results of a randomized crossover trial.

Probiotic Bif195 helps protect against aspirin-induced stomach damage

19 Jan 2024

Tacrolimus outclasses cyclosporine after liver transplantation for PSC

19 Jan 2024 by

Tacrolimus appears to be more effective than cyclosporine in improving patient and graft survival after liver transplantation (LT) for primary sclerosing cholangitis (PSC), results of a study have shown.

Tacrolimus outclasses cyclosporine after liver transplantation for PSC

19 Jan 2024

Linaclotide works well for functional constipation in children

19 Jan 2024

The guanylate cyclase C agonist linaclotide helps increase the frequency of bowel movements in children with functional constipation, according to data from a phase III trial.

Linaclotide works well for functional constipation in children

19 Jan 2024

Mirtazapine ups calorie consumption in NSCLC patients with anorexia

18 Jan 2024 by

In advanced nonsmall cell lung cancer (NSCLC) patients with anorexia, treatment with mirtazapine leads to a substantial increase in energy intake despite having no effect on appetite, as shown in a study.

Mirtazapine ups calorie consumption in NSCLC patients with anorexia

18 Jan 2024

Original New Drug Application Approvals by US FDA (01-15 January 2024)

18 Jan 2024

New drug applications approved by US FDA as of 01-15 January 2024 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.

Original New Drug Application Approvals by US FDA (01-15 January 2024)

18 Jan 2024

Adjuvant chemo confers no survival advantage following biliary tract cancer resection

18 Jan 2024

In older patients with resected biliary tract cancer, adjuvant chemotherapy does not appear to yield significant survival gains when compared with observation, according to a study.

Adjuvant chemo confers no survival advantage following biliary tract cancer resection

18 Jan 2024

Rituximab resolves complications in anti-MDA5–positive JDM

17 Jan 2024

Treatment with rituximab (RTX) in children with juvenile dermatomyositis (JDM) and antibodies to antimelanoma differentiation-associated gene 5 (anti-MDA5) results in clinical improvements in interstitial lung disease (ILD) as well as in cutaneous manifestation and musculoskeletal disease activity, according to a study.

Rituximab resolves complications in anti-MDA5–positive JDM

17 Jan 2024

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Vaccines protect liver disease patients against severe COVID-19

Vaccines protect liver disease patients against severe COVID-19

Shortened terlipressin therapy after endoscopic haemostasis as effective as 3-day course

Shortened terlipressin therapy after endoscopic haemostasis as effective as 3-day course

Linaclotide improves bowel movement frequency in children with functional constipation

Linaclotide improves bowel movement frequency in children with functional constipation

Probiotic Bif195 helps protect against aspirin-induced stomach damage

Probiotic Bif195 helps protect against aspirin-induced stomach damage

Tacrolimus outclasses cyclosporine after liver transplantation for PSC

Tacrolimus outclasses cyclosporine after liver transplantation for PSC

Linaclotide works well for functional constipation in children

Linaclotide works well for functional constipation in children

Mirtazapine ups calorie consumption in NSCLC patients with anorexia

Mirtazapine ups calorie consumption in NSCLC patients with anorexia

Original New Drug Application Approvals by US FDA (01-15 January 2024)

Original New Drug Application Approvals by US FDA (01-15 January 2024)

Adjuvant chemo confers no survival advantage following biliary tract cancer resection

Adjuvant chemo confers no survival advantage following biliary tract cancer resection

Rituximab resolves complications in anti-MDA5–positive JDM

Rituximab resolves complications in anti-MDA5–positive JDM