News & Updates

A recent study has found the proposed population risk stratification approach using the Steatosis-Associated Fibrosis Estimator (SAFE) score to be simpler and more effective than current guidelines.

Patients with autoimmune hepatitis (AIH) do not show an increased risk of overall extrahepatic malignancy compared with controls, but they appear to be at greater risk of lymphoma or myeloma, independent of immunosuppressant use, suggests a study.

In patients with synchronous metastatic renal cell carcinoma (mRCC), factors such as liver metastasis, increasing primary tumour size, and elevated preoperative C-reactive protein (CRP) predict the risk of first-year progression following cytoreductive nephrectomy and complete metastasectomy, suggests a recent study.

A novel risk score, named Cirrhosis Outcome Risk Estimator (CORE), performs better than FIB-4 in predicting liver-related outcomes in the general population, a study has shown. This model is based on a flexible modelling approach and utilizes biomarkers that are easily accessible in primary care.

Intake of even small amounts of alcohol appears to pose a significant health risk for East Asian men with metabolic dysfunction-associated steatotic liver disease (MASLD), according to a South Korean nationwide cohort study.

Genetic risk score (GRS), polygenic risk score-hepatic fat content (PRS-HFC), its adjusted version (PRS-5), and PNPLA3 genotypes alone show a significant relationship with increased fibrosis severity per decade in patients with metabolic dysfunction-associated steatotic liver disease (MASLD), reports a study.

Adding liver-directed radiation therapy (RT) to atezolizumab and bevacizumab (A/B) produces limited additional toxicity with higher response rates among patients with hepatocellular carcinoma (HCC), reports a recent study. However, substantial differences in baseline characteristics hinder a full interpretation of this data.

The use of direct oral anticoagulants (DOACs) appears to be safer than warfarin for patients with nonvalvular atrial fibrillation (AF) and liver cirrhosis (LC), suggests a study. This is particularly true to reducing the risk of major bleeding in those with Child-Pugh class A disease.

Simultaneous liver transplantation (LT) and sleeve gastrectomy (SG) is effective in sustaining weight loss, managing diabetes and hypertension, and preventing recurrence of steatosis and possibly fibrosis compared with LT alone, suggests a study.

Many patients with cirrhosis and acute kidney injury (AKI) need 2 days to show response to albumin treatment, a study has found. Therefore, reducing the duration of albumin therapy may result in overtreatment with terlipressin.