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What are the risk factors for relapse after methotrexate dose reduction?
For patients with rheumatoid arthritis, a history of cardiovascular disease, gastrointestinal disease, or liver disease, as well as prior use of nonsteroidal anti-inflammatory drugs can contribute to an increased risk of relapse after methotrexate dose reduction, as suggested in a study.

Vonoprazan-amoxicillin combo on par with B-quadruple therapy for H. pylori infection
Ten-day treatment with vonoprazan 20 mg twice/day plus amoxicillin 750 mg four times/day (VHA-dual) as a first-line therapy for Helicobacter pylori infection results in satisfactory eradication rate of >90 percent, fewer adverse events (AEs), and similar adherence when compared with bismuth quadruple therapy (B-quadruple), results of a study have shown.

Molnupiravir speeds up recovery, reduces viral load of vaccinated COVID-19 patients
In vaccinated adults with COVID-19 who are at higher risk of adverse outcomes, treatment with molnupiravir in addition to usual care falls short of reducing the rates of hospitalizations and deaths, as shown by the results of the PANORAMIC study.






