News & Updates

New users of sacubitril-valsartan (SV) show no increased risk of angioedema when compared to users of angiotensin-converting enzyme (ACE) inhibitor and angiotensin receptor blocker (ARB), reports a study.

An earlier onset of fever appears to predict a more severe and progressive cytokine release syndrome, a life-threatening hyper-inflammatory state caused by immune effector cell therapy, suggests a study. Such condition also warrants several doses of anti-interleukin (IL)-6 therapy, such as tocilizumab.

Women with vulvovaginal atrophy exhibit a less favourable vaginal microbiome than healthy postmenopausal women, but ospemifene may restore vaginal health by reducing potentially harmful bacteria, as shown in a study.

Treatment with proton therapy reirradiation for head and neck cancer appears to improve survival outcomes in patients, but this benefit comes with substantial toxic effects, according to a study.

Treatment with sodium-glucose cotransporter 2 (SGLT2) inhibitors appears to have the added benefit of reducing the incidence of obstructive airway disease (OAD) in Asian patients with type 2 diabetes (T2D), as shown in a study from Hong Kong.

One-time ex-vivo gene therapy with betibeglogene autotemcel (beti-cel) reduces the need for transfusion in patients with transfusion-dependent beta-thalassaemia in an analysis of studies presented at ASH 2022.