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Intracranial atherosclerosis disease linked to cognitive impairment, dementia

28 Nov 2023

Individuals with intracranial atherosclerosis disease (ICAD) have a heightened risk of cognitive impairment and dementia, according to the results of a systematic review and meta-analysis.

Intracranial atherosclerosis disease linked to cognitive impairment, dementia

28 Nov 2023

Zoledronate improves BMD of children with cerebral palsy

23 Nov 2023

Twelve-month treatment with zoledronate significantly increases bone mineral density (BMD) Z-scores without affecting growth in nonambulant children with cerebral palsy (CP), reports a study. However, side effects of the first dose are common.

Zoledronate improves BMD of children with cerebral palsy

23 Nov 2023

Dementia risk heightened after stopping metformin treatment

18 Nov 2023 by

Metformin treatment discontinuation has been found to lead to increased incidence of dementia among older adults, and this association cannot be explained by changes in glucose control or insulin use.

Dementia risk heightened after stopping metformin treatment

18 Nov 2023

Chronic HBV infection may up risk of intracerebral haemorrhage

17 Nov 2023

Chronic hepatitis B virus (HBV) infection appears to put Chinese adults at higher risk of intracerebral haemorrhage but not other stroke subtypes, as reported in a study.

Chronic HBV infection may up risk of intracerebral haemorrhage

17 Nov 2023

Strawberries may stave off dementia

12 Nov 2023 by

Strawberries can potentially contribute to the prevention of dementia, with a small study suggesting that supplementation with whole-fruit strawberry powder helps improve memory in middle-aged adults.

Strawberries may stave off dementia

12 Nov 2023

Lower chance of new stroke with ticagrelor vs clopidogrel in patients without ICAS

11 Nov 2023 by

A post hoc analysis of the CHANCE-2 randomized controlled trial (RCT) demonstrates that ticagrelor-aspirin combination therapy is associated with a significantly lower risk of new stroke within 90 days vs the clopidogrel-aspirin combination in Chinese CYP2C19 loss‐of‐function allele carriers with minor stroke or transient ischaemic attack (TIA) without intracranial artery stenosis (ICAS).

Lower chance of new stroke with ticagrelor vs clopidogrel in patients without ICAS

11 Nov 2023

Brexpiprazole improves agitation in Alzheimer’s dementia

09 Nov 2023 by

A double-blind, placebo-controlled, randomized clinical trial reports significant improvement in agitation with brexpiprazole vs placebo among patients with Alzheimer’s dementia.

Brexpiprazole improves agitation in Alzheimer’s dementia

09 Nov 2023

Brain-controlled ankle prosthesis promotes natural movement, stability

08 Nov 2023 by

Neural control of a robotic ankle prosthesis appears to help its users to employ mechanisms that the body naturally uses to maintain balance and stability, including ankle movements, for better postural control, as shown in a study.

Brain-controlled ankle prosthesis promotes natural movement, stability

08 Nov 2023

Original New Drug Application Approvals by US FDA (16-31 October 2023)

08 Nov 2023

New drug applications approved by US FDA as of 16-31 October 2023 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.

Original New Drug Application Approvals by US FDA (16-31 October 2023)

08 Nov 2023

Retinal artery occlusion carries risk of death, adverse cardiovascular events

30 Oct 2023

Individuals with retinal artery occlusion (RAO) may be at increased risk of death, stroke, and myocardial infarction (MI) both in the short and long term, according to a study.

Retinal artery occlusion carries risk of death, adverse cardiovascular events

30 Oct 2023

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Intracranial atherosclerosis disease linked to cognitive impairment, dementia

Intracranial atherosclerosis disease linked to cognitive impairment, dementia

Zoledronate improves BMD of children with cerebral palsy

Zoledronate improves BMD of children with cerebral palsy

Dementia risk heightened after stopping metformin treatment

Dementia risk heightened after stopping metformin treatment

Chronic HBV infection may up risk of intracerebral haemorrhage

Chronic HBV infection may up risk of intracerebral haemorrhage

Strawberries may stave off dementia

Strawberries may stave off dementia

Lower chance of new stroke with ticagrelor vs clopidogrel in patients without ICAS

Lower chance of new stroke with ticagrelor vs clopidogrel in patients without ICAS

Brexpiprazole improves agitation in Alzheimer’s dementia

Brexpiprazole improves agitation in Alzheimer’s dementia

Brain-controlled ankle prosthesis promotes natural movement, stability

Brain-controlled ankle prosthesis promotes natural movement, stability

Original New Drug Application Approvals by US FDA (16-31 October 2023)

Original New Drug Application Approvals by US FDA (16-31 October 2023)

Retinal artery occlusion carries risk of death, adverse cardiovascular events

Retinal artery occlusion carries risk of death, adverse cardiovascular events