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Lovo-cel gene therapy shows near-complete VOE resolution in sickle cell disease

04 Jan 2024 by

A single infusion of lovotibeglogene autotemcel (lovo-cel) resulted in near-complete resolution of vaso-occlusive events (VOEs) among patients with sickle cell disease (SCD), according to the combined analysis of phase I/II HGB-206 group C and phase III HGB-210 studies presented at ASH 2023.

Lovo-cel gene therapy shows near-complete VOE resolution in sickle cell disease

04 Jan 2024

Original New Drug Application Approvals by US FDA (16-31 December 2023)

03 Jan 2024

New drug applications approved by US FDA as of 16-31 December 2023 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.

Original New Drug Application Approvals by US FDA (16-31 December 2023)

03 Jan 2024

Mediterranean diet boosts fertility, averts poor pregnancy outcome

02 Jan 2024 by

Keeping to a Mediterranean diet improves fertility and averts poor pregnancy outcome in a comprehensive review and meta-analysis conducted by Singaporean researchers.

Mediterranean diet boosts fertility, averts poor pregnancy outcome

02 Jan 2024

Retinoblastoma treatment carries increased risk of neutropenia

30 Dec 2023

Neutropenia following intra-arterial chemotherapy occurs more frequently than previously reported among children with retinoblastoma, with topotecan possibly linked to a risk increase, according to a study.

Retinoblastoma treatment carries increased risk of neutropenia

30 Dec 2023

Remdesivir shows no clear benefit in children with severe COVID-19

25 Dec 2023 by

The antiviral remdesivir offers no clear benefit in the treatment of children with severe COVID-19, falling short of reducing the time spent in high dependency or intensive care unit (HD/ICU), according to a study from Singapore.

Remdesivir shows no clear benefit in children with severe COVID-19

25 Dec 2023

Children resilient to early adversity at risk for anxiety, depression in adulthood

25 Dec 2023

It is not common to see children who have resilience to early adversity, and those who appear to be resilient in childhood are at increased risk of delayed poorer outcomes in adulthood, suggests a study.

Children resilient to early adversity at risk for anxiety, depression in adulthood

25 Dec 2023

Should KD patients be screened for Yersinia infection?

22 Dec 2023

Routine screening for Yersinia infection is not recommended for patients with Kawasaki disease (KD), suggests a recent study.

Should KD patients be screened for Yersinia infection?

22 Dec 2023

Routine testing for enterovirus CNS infection a must in febrile infants: study

21 Dec 2023

Infants with human nonpolio enterovirus (EV) central nervous system (CNS) infection often present without cerebrospinal fluid (CSF) pleocytosis, reports a study.

Routine testing for enterovirus CNS infection a must in febrile infants: study

21 Dec 2023

Maternal rheumatoid arthritis carries risk of ASD in offspring

20 Dec 2023

Infants born to mothers with rheumatoid arthritis (RA) during pregnancy are at risk of autism spectrum disorder (ASD), according to a study.

Maternal rheumatoid arthritis carries risk of ASD in offspring

20 Dec 2023

Even seemingly healthy teens with high BMI at risk of early CKD

18 Dec 2023

High body mass index (BMI) in late adolescence appears to be a risk factor for chronic kidney disease (CKD) in young adulthood, even for seemingly healthy individuals with a BMI that falls within the normal range but is closer to the upper limit, as reported in a study.

Even seemingly healthy teens with high BMI at risk of early CKD

18 Dec 2023

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Lovo-cel gene therapy shows near-complete VOE resolution in sickle cell disease

Lovo-cel gene therapy shows near-complete VOE resolution in sickle cell disease

Original New Drug Application Approvals by US FDA (16-31 December 2023)

Original New Drug Application Approvals by US FDA (16-31 December 2023)

Mediterranean diet boosts fertility, averts poor pregnancy outcome

Mediterranean diet boosts fertility, averts poor pregnancy outcome

Retinoblastoma treatment carries increased risk of neutropenia

Retinoblastoma treatment carries increased risk of neutropenia

Remdesivir shows no clear benefit in children with severe COVID-19

Remdesivir shows no clear benefit in children with severe COVID-19

Children resilient to early adversity at risk for anxiety, depression in adulthood

Children resilient to early adversity at risk for anxiety, depression in adulthood

Should KD patients be screened for Yersinia infection?

Should KD patients be screened for Yersinia infection?

Routine testing for enterovirus CNS infection a must in febrile infants: study

Routine testing for enterovirus CNS infection a must in febrile infants: study

Maternal rheumatoid arthritis carries risk of ASD in offspring

Maternal rheumatoid arthritis carries risk of ASD in offspring

Even seemingly healthy teens with high BMI at risk of early CKD

Even seemingly healthy teens with high BMI at risk of early CKD