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Risk-reducing surgeries tied to improved outcomes in BRCA carriers with young-onset BC

20 Jan 2025 by

A large global study provides evidence that risk-reducing mastectomy (RRM) and/or risk-reducing salpingo-oophorectomy (RRSO) is associated with improved survival outcomes in young women diagnosed with breast cancer (BC) at or before 40 years of age who were harbouring germline BRCA1 and/or BRCA2 pathogenic variants (PVs).

Risk-reducing surgeries tied to improved outcomes in BRCA carriers with young-onset BC

20 Jan 2025

Novel drug for moderate-to-severe UC yields quality-of-life benefits

20 Jan 2025 by

RO7790121, an antibody against tumour necrosis factor-like ligand 1A (Anti-TL1A), helps improve the health-related quality of life (HR-QoL) for patients with moderately to severely active ulcerative colitis (UC), as shown in the phase IIb TUSCANY-2 trial.

Novel drug for moderate-to-severe UC yields quality-of-life benefits

20 Jan 2025

Noncigarette tobacco products carry distinct health risks

20 Jan 2025

The use of noncigarette tobacco products is associated with distinctive cardiovascular outcomes, including stroke for cigar, heart failure for pipe, and total cardiovascular disease (CVD) for smokeless tobacco, as shown in a study.

Noncigarette tobacco products carry distinct health risks

20 Jan 2025

Anti-TNFs may reduce GDM risk in pregnant women with IBD

19 Jan 2025

Pregnant women with inflammatory bowel disease (IBD) who used antitumour necrosis factor (anti-TNF) therapy are at reduced risk of developing gestational diabetes mellitus (GDM), reports a study.

Anti-TNFs may reduce GDM risk in pregnant women with IBD

19 Jan 2025

Hormone therapy poses no glioma risk

19 Jan 2025

Users of hormone therapy do not appear to be at increased risk of glioma, according to a study.

Hormone therapy poses no glioma risk

19 Jan 2025

Labour pain, complications drive early breastfeeding cessation

18 Jan 2025 by

Among breastfeeding mums in Singapore, those who had obstetric complications and experienced more pain during labour tend to stop sooner than the recommended 6 months, according to a study.

Labour pain, complications drive early breastfeeding cessation

18 Jan 2025

Making the case for paediatric one-day admission in SG

18 Jan 2025 by

One-day admissions for paediatric patients may offer ways to help prevent hospital congestion, suggests a Singapore study.

Making the case for paediatric one-day admission in SG

18 Jan 2025

Twice-yearly depemokimab tied to fewer severe asthma exacerbations

18 Jan 2025

In the treatment of severe asthma with an eosinophilic phenotype, 6-month dosing intervals of depemokimab appears to reduce the rate of exacerbations, as shown in a phase IIIA study.