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Sofosbuvir/velpatasvir effective, safe for paediatric HCV
The direct-acting antiviral (DAA) sofosbuvir/velpatasvir (SOF/VEL) was effective and safe for the treatment of chronic hepatitis C virus (HCV) infection in individuals aged 6–18 years, the PANDAA-PED study has shown.

2-dose, 3-dose vax schedules active against several meningococcal serogroup B strains
Both the 2-dose and 3-dose vaccination schedules of the four-component meningococcal serogroup B vaccine (4CMenB) appear to provide protection against a panel epidemiologically relevant strains in adolescents and young adults, according to a phase III study presented at ESPID 2023.

SGLT2 inhibitors reduce HCC risk in T2DM patients with CHB
The use of sodium-glucose cotransporter 2 (SGLT2) inhibitors is associated with a reduced risk of incident hepatocellular carcinoma (HCC) in patients with coexisting type 2 diabetes mellitus (T2DM) and chronic hepatitis B (CHB), a territory-wide cohort study in Hong Kong has shown.

Weight gain persists, obesity rises in children after pandemic lockdown
Some children, particularly boys, continue to gain weight even after COVID-19 pandemic lockdown measures have been eased, indicating the challenges in reversing the effects of lockdowns, reveals a study in Argentina. However, sedentary behaviours have decreased while quality of life has improved.

Influenza vaccine wards off cardiovascular events, death in CAD patients
A meta-analysis of randomized trials has revealed that influenza vaccination is effective at preventing all-cause mortality, cardiovascular mortality, major acute cardiovascular events, and acute coronary syndrome (ACS) among patients with coronary artery disease (CAD), particularly in those with ACS.



