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DeLLphi-304: Tarlatamab bests SoC chemo as 2L treatment for SCLC

07 Aug 2025 by

Tarlatamab was associated with significant improvements in overall survival (OS), progression-free survival (PFS) and patient-reported outcomes (PROs) vs standard-of-care (SoC) chemotherapy in patients with small-cell lung cancer (SCLC) undergoing second-line (2L) therapy, according to the primary analysis of the phase III DeLLphi-304 study presented at ASCO 2025.

DeLLphi-304: Tarlatamab bests SoC chemo as 2L treatment for SCLC

07 Aug 2025

More walking, less low back pain issues

06 Aug 2025 by

Walking a longer distance or for a longer time can reduce the risk of developing chronic low back pain.

More walking, less low back pain issues

06 Aug 2025

Sexual function reduced in people with multiple sclerosis

06 Aug 2025

People with multiple sclerosis (MS) tend to experience a lower sexual function (SF) than healthy individuals, reports a study. Age, depression, disease duration, and the Expanded Disability Status Scale (EDSS) influence SF.

Sexual function reduced in people with multiple sclerosis

06 Aug 2025

POIS treatment must consider symptoms, outcomes: study

06 Aug 2025 by

Examining the symptoms experienced by patients with postorgasmic illness syndrome (POIS) can help improve treatment and resolve these symptoms, suggests a study.

POIS treatment must consider symptoms, outcomes: study

06 Aug 2025

Vedolizumab vs adalimumab: Which works better for CD?

06 Aug 2025 by

Treatment with vedolizumab exhibits equivalent rates of response and mucosal healing but higher odds of drug persistence and achieving clinical remission compared with adalimumab in biologic-naïve patients with Crohn’s disease (CD), reports a study in a real-world setting.

Vedolizumab vs adalimumab: Which works better for CD?

06 Aug 2025

Rehydration strategies yield similar mortality outcome in kids with malnutrition, gastroenteritis

06 Aug 2025

In the treatment of children with severe acute malnutrition and gastroenteritis, those who undergo oral rehydration therapy have similar mortality rates as those who receive intravenous rehydration therapy, according to a study.

Rehydration strategies yield similar mortality outcome in kids with malnutrition, gastroenteritis

06 Aug 2025

Scheduled lorazepam-based regimens superior to haloperidol alone for agitated delirium at end of life

06 Aug 2025 by

Proactive use of scheduled lorazepam or lorazepam plus haloperidol is superior to haloperidol alone in managing refractory agitated delirium in patients with advanced cancer in the palliative care setting, according to results of a multicentre randomized clinical trial (RCT) conducted in Taiwan and the US.

Scheduled lorazepam-based regimens superior to haloperidol alone for agitated delirium at end of life

06 Aug 2025

Hidradenitis suppurativa patients vulnerable to mental disorders

05 Aug 2025 by

Patients with hidradenitis suppurativa (HS) face increased risks of depression and anxiety, as reported in a study.

Hidradenitis suppurativa patients vulnerable to mental disorders

05 Aug 2025

Healthy behaviours may prevent death in cirrhosis patients

05 Aug 2025

Keeping a healthy lifestyle such as having a balanced diet, regular exercise, and quality sleep may provide survival benefits to patients with cirrhosis, suggests a study.

Healthy behaviours may prevent death in cirrhosis patients

05 Aug 2025

Awareness, linkage to care may motivate people with HCV to seek treatment

05 Aug 2025 by

Nearly one in five hepatitis C virus (HCV) infections in the last decade have been treated with direct-acting antivirals (DAAs), as well as about a third of the target population, according to a study.

Awareness, linkage to care may motivate people with HCV to seek treatment

05 Aug 2025

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DeLLphi-304: Tarlatamab bests SoC chemo as 2L treatment for SCLC

DeLLphi-304: Tarlatamab bests SoC chemo as 2L treatment for SCLC

More walking, less low back pain issues

More walking, less low back pain issues

Sexual function reduced in people with multiple sclerosis

Sexual function reduced in people with multiple sclerosis

POIS treatment must consider symptoms, outcomes: study

POIS treatment must consider symptoms, outcomes: study

Vedolizumab vs adalimumab: Which works better for CD?

Vedolizumab vs adalimumab: Which works better for CD?

Rehydration strategies yield similar mortality outcome in kids with malnutrition, gastroenteritis

Rehydration strategies yield similar mortality outcome in kids with malnutrition, gastroenteritis

Scheduled lorazepam-based regimens superior to haloperidol alone for agitated delirium at end of life

Scheduled lorazepam-based regimens superior to haloperidol alone for agitated delirium at end of life

Hidradenitis suppurativa patients vulnerable to mental disorders

Hidradenitis suppurativa patients vulnerable to mental disorders

Healthy behaviours may prevent death in cirrhosis patients

Healthy behaviours may prevent death in cirrhosis patients

Awareness, linkage to care may motivate people with HCV to seek treatment

Awareness, linkage to care may motivate people with HCV to seek treatment