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Nonoperative management safe, feasible after complete response in rectal cancer

15 Jul 2022

Patients with locally advanced rectal cancer who achieve complete response (CR) following sequential short-course radiation therapy (SCRT) and chemotherapy appear to benefit from nonoperative management (NOM) with a watch-and-wait strategy, which presents evidence for good anorectal functions, results of a study have shown.

Nonoperative management safe, feasible after complete response in rectal cancer

15 Jul 2022

SI-TEAS intervention eases cancer-related fatigue, improves cell immunity

15 Jul 2022 by

Somatosensory interaction transcutaneous electrical acupoint stimulation (SI-TEAS), an emerging traditional Chinese medicine nursing practice, is effective in relieving cancer-related fatigue (CRF) and improving a tumour patient’s cell immunity, a study has found.

SI-TEAS intervention eases cancer-related fatigue, improves cell immunity

15 Jul 2022

GI practitioners cease PPI use in patients due to concerns of side effects

15 Jul 2022

Discontinuation of proton pump inhibitor (PPI) use remains prevalent, even within a group of mostly academic gastroenterology (GI) practitioners, despite evidence suggesting the safety of long-term PPI use without routine monitoring, a study has shown.

GI practitioners cease PPI use in patients due to concerns of side effects

15 Jul 2022

Concomitant azole use may influence bleeding risk in AF patients on NOACs

15 Jul 2022 by

In a study evaluating azole use in patients with atrial fibrillation (AF) on non-vitamin K antagonist oral anticoagulants (NOACs), systemic exposure to the antifungal agent fluconazole was associated with an elevated risk of bleeding, particularly among those on apixaban. Conversely, no association was seen between NOACs and topical azoles*.

Concomitant azole use may influence bleeding risk in AF patients on NOACs

15 Jul 2022

Three layers of stigma prevent mental health recovery in Singapore

15 Jul 2022 by

Internalized stigma, compounded by public, structural, and systemic stigmas pose substantial barriers to recovery among persons with mental illnesses (PMI), according to a recent Singapore study.

Three layers of stigma prevent mental health recovery in Singapore

15 Jul 2022

Olaparib safe, effective in ovarian cancer patients with BRCA mutation, HRD

15 Jul 2022

Olaparib demonstrates clinical activity across patients with platinum-sensitive relapsed ovarian cancer and known BRCA mutation and homologous recombination deficiency (HRD), as shown in the phase II LIGHT study.

Olaparib safe, effective in ovarian cancer patients with BRCA mutation, HRD

15 Jul 2022

Genes for elevated blood pressure contribute to pre-eclampsia risk

15 Jul 2022

Genetic predisposition to high blood pressure appears to heighten the risks of pre-eclampsia, recurrent pre-eclampsia, and pre-eclampsia with severe features, a study has found.