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Add-on ribociclib continues to triumph in early breast cancer
Coming on the heels of the second interim analysis, the protocol-specified final invasive disease-free survival (iDFS) analysis of the phase III NATALEE trial continues to show a highly significant iDFS benefit with the combination of the CDK 4/6 inhibitor ribociclib and a nonsteroidal aromatase inhibitor (NSAI) in individuals with HR+/HER2- early breast cancer.
Add-on ribociclib continues to triumph in early breast cancer
20 Dec 2023MONARCH 3 final OS data support abemaciclib-NSAI for HR+/HER2- advanced breast cancer
In the final overall survival (OS) analysis of the phase III MONARCH 3 trial, the combination of the CDK 4/6 inhibitor abemaciclib and a nonsteroidal aromatase inhibitor (NSAI) continued to show clinically meaningful signals as first-line (1L) treatment for HR+/HER2- advanced breast cancer.
MONARCH 3 final OS data support abemaciclib-NSAI for HR+/HER2- advanced breast cancer
18 Dec 2023Cholesterol-rich diet, variants of metabolism genes predict GDM development
A diet rich in cholesterol during early pregnancy and genetic variations of cholesterol metabolism genes both contribute to the risk of gestational diabetes mellitus (GDM), suggests a study.