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Add-on trilaciclib boosts antitumour effects of chemo combinations for triple-negative breast cancer
Pretreatment with the cyclin-dependent kinase 4/6 inhibitor trilaciclib appears to enhance the antitumour efficacy of gemcitabine plus carboplatin, with significant survival gains for patients with metastatic triple-negative breast cancer (mTNBC), according to the results of a phase II trial.
Add-on trilaciclib boosts antitumour effects of chemo combinations for triple-negative breast cancer
24 Feb 2022Lenvatinib-TACE combo a new first-line treatment alternative for advanced liver cancer?
In individuals with advanced hepatocellular carcinoma (HCC), the combination of transarterial chemoembolization (TACE) and lenvatinib as first-line treatment led to improved survival outcomes as opposed to lenvatinib monotherapy, according to findings of the phase III LAUNCH* trial.
Lenvatinib-TACE combo a new first-line treatment alternative for advanced liver cancer?
23 Feb 2022Serrated polyposis syndrome patients, relatives at risk of colorectal cancer
The risk of colorectal cancer (CRC) is heightened in patients with serrated polyposis syndrome (SPS) and their first-degree relatives (FDRs), according to a study, which confirms findings of other reports. In addition, those with sessile serrated lesions (SSL) are at higher of prostate cancer.
Serrated polyposis syndrome patients, relatives at risk of colorectal cancer
21 Feb 2022Ongoing anticancer treatment dulls immune response against COVID-19
Therapy-naïve patients with haematological malignancies are able to mount a stronger immune response to the coronavirus disease 2019 (COVID-19), a recent study has found.
Ongoing anticancer treatment dulls immune response against COVID-19
19 Feb 2022Ixazomib dexamethasone a new treatment in the arsenal against RRMM
In heavily pretreated, lenalidomide-refractory patients with relapsed-refractory multiple myeloma (RRMM) and prior exposure to proteasome inhibitors, ixazomib dexamethasone may be an effective and tolerable treatment approach, leading to comparable health-related quality of life outcomes as pomalidomide-dexamethasone, a recent study has found.
Ixazomib dexamethasone a new treatment in the arsenal against RRMM
18 Feb 2022Patient-reported outcomes tied to healthcare use in NDMM
Patient-reported outcome measures may help predict healthcare utilization, such as emergency department visits or unplanned hospitalizations, among patients with transplant-ineligible newly diagnosed multiple myeloma (NDMM), a recent study has found.
Patient-reported outcomes tied to healthcare use in NDMM
16 Feb 2022Trastuzumab biosimilar on par with reference agent in HER2-positive gastric cancer
CT-P6, a trastuzumab biosimilar approved for the treatment of human epidermal growth factor receptor 2 (HER2)-positive advanced gastric cancer (AGC), is as efficacious as reference trastuzumab in terms of response rates, progression-free (PFS) and overall survival (OS), a study has shown.