News &amp; Updates

Use of cyclosporine A cationic emulsion 0.1% eye drops in the treatment of patients with severe active vernal keratoconjunctivitis is safe and yields improvements in keratitis, symptoms and quality of life that are maintained for up to 8 months, according to the results of a trial.

Cyclosporine emulsion holds potential in vernal keratoconjunctivitis

Tucatinib-based therapy improves PFS and OS in heavily pretreated HER2-positive metastatic breast cancer

07 Jan 2020 by

Adding the oral HER2-targeted tyrosine kinase inhibitor (TKI) tucatinib to trastuzumab-capecitabine combination therapy significantly improves progression-free survival (PFS) and overall survival (OS) in patients with heavily pretreated HER2-positive metastatic breast cancer, including those with brain metastases, results of the HER2CLIMB trial have shown.

Tucatinib-based therapy improves PFS and OS in heavily pretreated HER2-positive metastatic breast cancer

Cilostazol suitable for certain stroke patients with diffuse fragile small-vessel disease

07 Jan 2020 by

Asian ischaemic stroke patients with small and fragile cerebral vessels, as evidenced by the presence of multiple cerebral microbleeds (CMBs), may fare better with cilostazol than aspirin, as the former proves more effective at preventing cerebral haemorrhages especially when administered before white matter changes become extensive, according to the results of a subgroup analysis of the PICASSO* trial.

Cilostazol suitable for certain stroke patients with diffuse fragile small-vessel disease

Adding evolocumab atop statin cuts LDL-C in high-risk ACS

06 Jan 2020 by

In-hospital initiation of the PCSK9* inhibitor evolocumab, on top of high-intensity statin therapy, in the very high-risk, acute phase of ACS** significantly reduced LDL-C levels — so much so that >95 percent of the patients achieved the recommended target levels — compared with high-intensity statin alone, the EVOPACS*** study has shown.

Adding evolocumab atop statin cuts LDL-C in high-risk ACS

Squaric acid dibutylester topical immunotherapy works against alopecia areata

Topical immunotherapy with squaric acid dibutylester appears to be effective in the treatment of alopecia areata, according to a study, lending support to current treatment guidelines recommending the use of topical immunotherapies.

Squaric acid dibutylester topical immunotherapy works against alopecia areata

Deprescribing of acetyle cholinesterase inhibitors safe for patients with severe dementia

Deprescribing acetyl cholinesterase inhibitors (AChEIs) in elderly adults with severe dementia does not appear to result in the occurrence of negative events, a recent study has shown.

Deprescribing of acetyle cholinesterase inhibitors safe for patients with severe dementia

Fitness trackers improve fatigue, but not HRQoL, in breast cancer survivors

06 Jan 2020 by

Wearable activity trackers improve physical activity and cut sedentary time in breast cancer survivors, but do not appear to bear significant benefits on health-related quality of life (HRQoL), according to a new study.

Fitness trackers improve fatigue, but not HRQoL, in breast cancer survivors

Target organ damage more pronounced in patients with primary aldosteronism

Target organ damage appears to be more noticeable in patients affected by primary aldosteronism than those affected by arterial hypertension without primary aldosteronism, suggests a study, adding that specific treatment can ease such condition.

Target organ damage more pronounced in patients with primary aldosteronism

$Cow’s milk offers little in terms of lowering fracture risk in childhood$

Cow’s milk offers little in terms of lowering fracture risk in childhood

Neither the volume nor the fat content consumed from cow’s milk in early life helps protect against the risk of developing fractures in later childhood, a study has found.

Cow’s milk offers little in terms of lowering fracture risk in childhood

Electronic medical records may facilitate early assessment of ADRD risk

Electronic medical records (EMR) may help in the early identification of the likelihood of Alzheimer’s disease and related dementias (ADRD), a recent study has found.

Electronic medical records may facilitate early assessment of ADRD risk