News &amp; Updates

Achieving multifactorial targets for blood pressure (BP), low-density lipoprotein-cholesterol (LDL-C), HbA1c and current smoking greatly benefits patients with and without diabetes mellitus (DM) and is associated with a reduced risk for coronary artery disease (CAD), a study has shown.

Controlling multiple risk factors lowers CAD risk in diabetic patients

Silver bullet against HFpEF remains elusive

Treatment options for patients with heart failure with preserved ejection fraction (HFpEF) remain limited, with benefits that are marginal at best, according to Prof Michel Komajda, past president of the European Society of Cardiology (ESC), at their recently concluded 2019 Asia Congress (ESC Asia 2019).

Silver bullet against HFpEF remains elusive

CABG most effective for multivessel disease among diabetics in FREEDOM trial

Coronary artery bypass grafting (CABG) reduces the risk nonfatal myocardial infarction (MI) and major adverse cardiovascular events (MACE) among diabetes mellitus (DM) patients with multivessel disease (MVD), according to a recent study presented at the Asia Congress of the European Society of Cardiology (ESC Asia 2019).

CABG most effective for multivessel disease among diabetics in FREEDOM trial

Fluid overload in paediatric sepsis/septic shock patients tied to poor outcomes

Excessive fluid administration within the first 5 days in the paediatric intensive care unit (PICU) was consistently and independently associated with poor clinical outcomes in children with severe sepsis and septic shock, a Singapore study has shown.

Fluid overload in paediatric sepsis/septic shock patients tied to poor outcomes

Influenza worsens AMI outcomes

Patients with acute myocardial infarction (AMI) are likely to suffer from worse clinical outcomes in the presence of influenza and other viral infections, a recent study has shown.

Influenza worsens AMI outcomes

Active disease, reduced physical function negatively influence work productivity in axSpA patients

Among patients with axial spondyloarthritis (axSpA) in Singapore, work productivity is lower in the presence of active disease, reduced physical function and poorer quality of life, as reported in a Singapore study.

Active disease, reduced physical function negatively influence work productivity in axSpA patients

Microwave ablation: A better minimally invasive technique for HCC?

A systematic review and meta-analysis evaluating two percutaneous ablation techniques – microwave ablation (MWA) and radiofrequency ablation (RFA) – showed that the former fared better than the latter in reducing local tumour progression (LTP) rates in individuals with hepatocellular carcinoma (HCC) and/or liver metastases.

Microwave ablation: A better minimally invasive technique for HCC?

Aclidinium bromide safe for COPD patients regardless of exacerbation history

12 Nov 2019 by

The LAMA* aclidinium bromide was similarly effective in reducing exacerbation rate without raising the risk of MACE** or all-cause mortality regardless of recent history of exacerbations in patients with moderate-to-very severe chronic obstructive pulmonary disease (COPD), according to a subgroup analysis of the phase IV ASCENT-COPD*** trial presented at the CHEST 2019 Annual Meeting.

Aclidinium bromide safe for COPD patients regardless of exacerbation history

Elderly myocardial infarction patients benefit from 2 years of statins

The use of statins is beneficial in elderly patients after their first myocardial infarction (MI) episode, particularly if medication is sustained for at least 2 years, a recent study has shown.

Elderly myocardial infarction patients benefit from 2 years of statins

Omega-3, vitamin D no help for kidney function: Time to shift attention

12 Nov 2019 by

Supplementation with omega-3 fatty acids or vitamin D3 for up to 5 years has no effect on kidney function in adults with type 2 diabetes (T2D), the VITAL-DKD* ancillary study has shown.

Omega-3, vitamin D no help for kidney function: Time to shift attention