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HEART-FID confirms IV iron safety for HF but falls short in efficacy
11 Sep 2023
byAudrey Abella
The HEART-FID trial narrowly missed its primary endpoint, showing modest improvement in all-cause mortality, heart failure hospitalizations (hHF), and exercise function with ferric carboxymaltose (FCM) in HFrEF* patients with iron deficiency (ID).
HEART-FID confirms IV iron safety for HF but falls short in efficacy
11 Sep 2023SMAD7 overexpression boosts EGFR-CAR-T function against NSCLC
10 Sep 2023
Epidermal growth factor receptor (EGFR)-mothers against decapentaplegic homologue 7 (SMAD7)-Chimeric antigen receptor (CAR) T-cell therapy against nonsmall-cell lung cancer (NSCLC) is on a par with EGFR-dominant‒negative transforming growth factor (TGFbeta) receptor 2 (DNR)-CAR-T in terms of efficacy and resistance to negative TGFβ regulation, a study has shown.