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PCSK9 inhibition tied to decreased psoriasis risk
Inhibition of the proprotein convertase subtilisin/kexin type 9 (PCSK9) pathway appears to be causally associated with a lower risk of psoriasis, regardless of the concentration levels of circulating low-density lipoprotein (LDL), according a two-sample Mendelian randomization study.
PCSK9 inhibition tied to decreased psoriasis risk
20 Mar 2023
Which factors predict progression from discoid lupus to severe SLE?
A diagnosis of discoid lupus erythematosus (DLE) at age 25 years or below, phototype V to VI, and antinuclear antibody titers of ≥1:320 are significantly associated with the development of severe systemic lupus erythematosus (SLE), according to a study.
Which factors predict progression from discoid lupus to severe SLE?
14 Mar 2023
Neoadjuvant–adjuvant bests adjuvant-only pembrolizumab in advanced melanoma
For patients with stage III or IV melanoma, treatment with pembrolizumab both before and after surgical resection leads to longer event-free survival than treatment with pembrolizumab only after the procedure, according to the results of a phase II study.
Neoadjuvant–adjuvant bests adjuvant-only pembrolizumab in advanced melanoma
14 Mar 2023
What are the signs of HSV infection in patients with pemphigus vulgaris?
Clinicians must be aware of the likelihood of infection with herpes simplex virus (HSV) in the presence of fissures, haemorrhagic crusts, linear erosions, erosions with angulated margins, and increased erythrocyte sedimentation rate among patients with pemphigus vulgaris, suggests a study.
What are the signs of HSV infection in patients with pemphigus vulgaris?
13 Mar 2023
Smoking cessation, preventing obesity help reduce psoriasis risk
The incidence of psoriasis may be decreased by maintaining a normal weight and by putting a stop to the use of tobacco and cigarettes, a recent study has shown. In addition, addressing the inequality in education may help lower the cases of this condition.
Smoking cessation, preventing obesity help reduce psoriasis risk
11 Mar 2023
Outpatient oritavancin bests inpatient SoC in acute uncomplicated cellulitis
Outpatient oritavancin therapy appears to be more effective than inpatient standard-of-care (SoC) in reducing 30-day hospital readmissions or admissions among individuals with acute uncomplicated cellulitis, a recent study has shown.
Outpatient oritavancin bests inpatient SoC in acute uncomplicated cellulitis
15 Feb 2023
Dupilumab yields rapid, lasting improvement in erythrodermic atopic dermatitis
Treatment with dupilumab helps improve the signs and symptoms of erythrodermic atopic dermatitis, with the improvements occurring as early as the first week and being sustained over time, according to a study. The drug has an acceptable safety profile.
Dupilumab yields rapid, lasting improvement in erythrodermic atopic dermatitis
04 Feb 2023
Oral ritlecitinib safe, effective for treatment of active nonsegmental vitiligo
Treatment with oral ritlecitinib improves outcomes in patients with active nonsegmental vitiligo, without any serious adverse events over 48 weeks, results of a study have shown.
Oral ritlecitinib safe, effective for treatment of active nonsegmental vitiligo
27 Jan 2023
Online on par with in-person care for improving outcomes in psoriasis
An online health model appears to be as effective as in-person care for decreasing functional impairment and depressive symptoms in patients with psoriasis, according to a study.