News &amp; Updates

Female patients with colon cancer experience significantly greater toxicity with adjuvant chemotherapy compared with their male counterparts, a study has found.

Increased toxicity seen in women receiving adjuvant chemo for colon cancer

IGF-1 to IGFBP-2 ratio ≤0.85 a strong indicator of pancreatic adenocarcinoma

07 Oct 2020 by

Insulin-like growth factor 1 (IGF-1) to insulin-like growth factor–binding protein 2 (IGFBP-2) ratio ≤0.85 appears to be a useful biomarker in the diagnosis of pancreatic adenocarcinoma (PDAC), suggests a recent study.

IGF-1 to IGFBP-2 ratio ≤0.85 a strong indicator of pancreatic adenocarcinoma

Low adherence to febrile neutropaenia guidelines leads to hospitalization, over-prescription

A recent study has found low adherence to the febrile neutropaenia guidelines, which results in unnecessary hospital admissions of low-risk patients and over-prescription of empirical vancomycin.

Low adherence to febrile neutropaenia guidelines leads to hospitalization, over-prescription

BEACON CRC: Strategies to manage treatment-related AEs

06 Oct 2020 by

Several strategies have been proposed to help manage the adverse events (AEs) that emerged during the BEACON CRC trial which assessed the effect of encorafenib plus cetuximab in patients with BRAF V600E mutant metastatic colorectal cancer (mCRC) who had progressed after one or two prior regimens.

BEACON CRC: Strategies to manage treatment-related AEs

Which mask type is most effective for handling anticancer drug?

Measurement of the leak rate of masks used in anticancer drug handling confirms a significant difference, with the cup-type activated carbon mask showing effectiveness based on its low leak rate, suggest the results of a study.

Which mask type is most effective for handling anticancer drug?

Inflammatory potential of diet may not exacerbate bladder cancer risk

There appears to be no link between the inflammatory potential of diets and the risk of developing bladder cancer, a recent study has found.

Inflammatory potential of diet may not exacerbate bladder cancer risk

Cancer an important stroke risk factor in kids

Children with cancer are at a higher risk of developing stroke and may benefit from targeted prevention strategies, a new study has found.

Cancer an important stroke risk factor in kids

First-line chemo plus necitumumab improves overall survival in advanced NSCLC

Adding necitumumab to standard chemotherapy in a first-line setting significantly improves overall survival in patients with stage IV nonsmall cell lung cancer (NSCLC), a study has shown. However, results for progression-free survival (PFS) and objective response rate (ORR) are not statistically significant.

First-line chemo plus necitumumab improves overall survival in advanced NSCLC

$Post-op hypofractionated RT noninferior to conventional RT for early-stage breast cancer$

Post-op hypofractionated RT noninferior to conventional RT for early-stage breast cancer

05 Oct 2020 by

Hypofractionated radiotherapy (HFRT) followed by HF tumour bed-boost may have similar tumour control without an increase in toxicities compared with conventional fractionated radiotherapy (CFRT) in patients with breast cancer after breast-conserving surgery (BCS), results of a multicentre, randomized, controlled trial have shown.

Post-op hypofractionated RT noninferior to conventional RT for early-stage breast cancer

GCSF primary prophylaxis reduces febrile neutropenia and hospitalization in docetaxel-treated breast cancer patients

05 Oct 2020 by

The use of granulocyte colony-stimulating factors (GCSFs) as primary prophylaxis (PP) reduces the incidence of febrile neutropenia (FN) and associated hospitalization among breast cancer patients receiving docetaxel-containing chemotherapy, with 4–5 days of PP offering similar efficacy and greater healthcare expenditure savings vs 7-day PP, results of a retrospective cohort study in Hong Kong have shown.

GCSF primary prophylaxis reduces febrile neutropenia and hospitalization in docetaxel-treated breast cancer patients