News & Updates

Persistent ALT elevation triples risk of future T2D among overweight, obese children

30 Jun 2022 by

Children with overweight or obesity risk developing future type 2 diabetes (T2D) by threefold in the presence of persistent elevations in alanine aminotransferases (ALT), according to a study presented at the 54th Annual Meeting of the European Society for Paediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN 2022).

Persistent ALT elevation triples risk of future T2D among overweight, obese children

30 Jun 2022

Medication-assisted therapy tied to arrhythmia in patients with opioid use disorder

30 Jun 2022

In patients diagnosed with opioid use disorders, those who received medication-assisted therapy (MAT) prescriptions have a higher risk of cardiac arrhythmia than those who did not, reports a study.

Medication-assisted therapy tied to arrhythmia in patients with opioid use disorder

30 Jun 2022

Methotrexate proven safe, effective as first-line immunomodulator in paediatric CD

30 Jun 2022 by

Use of methotrexate (MTX) appears safe and effective as first-line immunomodulator for maintenance therapy in children with Crohn’s disease (CD), suggests a study presented at the 54th Annual Meeting of the European Society for Paediatric Gastroenterology, Hepatology, and Nutrition (ESPGHAN 2022).

Methotrexate proven safe, effective as first-line immunomodulator in paediatric CD

30 Jun 2022

Antioxidant cocktail works against diabetic polyneuropathy in T2D

30 Jun 2022

Treatment with a combination of succinic acid, inosine, nicotinamide, and riboflavin (SINR) is safe and alleviates the symptoms of diabetic polyneuropathy in patients with type 2 diabetes (T2D), according to data from the CYLINDER study.

Antioxidant cocktail works against diabetic polyneuropathy in T2D

30 Jun 2022

Original New Drug Application Approvals by US FDA (16 - 30 June 2022)

30 Jun 2022

New drug applications approved by US FDA as of 16 - 30 June 2022 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.

Original New Drug Application Approvals by US FDA (16 - 30 June 2022)

30 Jun 2022

Varenicline helps T2D patients quit smoking

29 Jun 2022 by

Use of varenicline in a smoking cessation program for patients with type 2 diabetes (T2D) is safe and effective, facilitating long-term abstinence without adverse consequences, according to the results of a trial.

Varenicline helps T2D patients quit smoking

29 Jun 2022

Muscle mass influences paclitaxel systemic exposure, informs personalized dosing

29 Jun 2022

Extending the infusion duration of paclitaxel in breast cancer patients with low skeletal muscle area is expected to reduce peripheral neuropathy while maintaining systemic exposure, suggests a study.

Muscle mass influences paclitaxel systemic exposure, informs personalized dosing

29 Jun 2022

Oral contraceptive, hormone replacement therapy pose increased stroke risk

29 Jun 2022

The use of oral contraceptive and hormone replacement therapy may put women at heightened risk of stroke, especially within the first year of use, possibly due to immediate changes in haemostatic balance, according to a study.

Oral contraceptive, hormone replacement therapy pose increased stroke risk

29 Jun 2022

Number of prior caesarean deliveries tied to complication risk following second-trimester abortion

29 Jun 2022

While induction in the second trimester for abortion or foetal demise can be safely performed for most women with prior caesarean deliveries, the risk of complications is increased for women with two or more prior caesarean deliveries, a study has found.

Number of prior caesarean deliveries tied to complication risk following second-trimester abortion

29 Jun 2022

$Prucalopride offers relief in children with refractory idiopathic constipation$

Prucalopride offers relief in children with refractory idiopathic constipation

28 Jun 2022 by

Three out of five teens with refractory constipation achieve improvements in bowel movement with prucalopride, while having acceptable side effect profiles, as shown in a small study.

Prucalopride offers relief in children with refractory idiopathic constipation

28 Jun 2022

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Persistent ALT elevation triples risk of future T2D among overweight, obese children

Persistent ALT elevation triples risk of future T2D among overweight, obese children

Medication-assisted therapy tied to arrhythmia in patients with opioid use disorder

Medication-assisted therapy tied to arrhythmia in patients with opioid use disorder

Methotrexate proven safe, effective as first-line immunomodulator in paediatric CD

Methotrexate proven safe, effective as first-line immunomodulator in paediatric CD

Antioxidant cocktail works against diabetic polyneuropathy in T2D

Antioxidant cocktail works against diabetic polyneuropathy in T2D

Original New Drug Application Approvals by US FDA (16 - 30 June 2022)

Original New Drug Application Approvals by US FDA (16 - 30 June 2022)

Varenicline helps T2D patients quit smoking

Varenicline helps T2D patients quit smoking

Muscle mass influences paclitaxel systemic exposure, informs personalized dosing

Muscle mass influences paclitaxel systemic exposure, informs personalized dosing

Oral contraceptive, hormone replacement therapy pose increased stroke risk

Oral contraceptive, hormone replacement therapy pose increased stroke risk

Number of prior caesarean deliveries tied to complication risk following second-trimester abortion

Number of prior caesarean deliveries tied to complication risk following second-trimester abortion

Prucalopride offers relief in children with refractory idiopathic constipation

Prucalopride offers relief in children with refractory idiopathic constipation