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Neoadjuvant olaparib feasible in BRCA-mutated ovarian cancer
Neoadjuvant treatment with the PARP* inhibitor olaparib yielded encouraging outcomes in patients with BRCA-mutated ovarian cancer, with all participants completing two cycles of therapy followed by surgery in the NOW trial presented at SGO 2023.
Neoadjuvant olaparib feasible in BRCA-mutated ovarian cancer
23 May 2023LIBERTY-UC: Maintenance subcutaneous infliximab eases moderate-to-severe UC
The subcutaneous infliximab formulation CT-P13 appears beneficial in the maintenance treatment of patients with moderately to severely active ulcerative colitis (UC), with data from the phase III study LIBERTY-UC showing that the drug outperforms placebo in multiple endpoints.
LIBERTY-UC: Maintenance subcutaneous infliximab eases moderate-to-severe UC
22 May 2023Rheumatologists need to match patient’s health literacy, says study
Communication between physicians and patients with systemic lupus erythematosus (SLE) leaves a lot to be desired, with a recent study suggesting that rheumatologists must beef up communication to match the health literacy (HL) of their patients. Doing so may foster trust and improve self-management and outcomes in SLE.
Rheumatologists need to match patient’s health literacy, says study
22 May 2023Natriuretic response to acetazolamide predicts decongestion in acute heart failure
A robust association exists between increased natriuresis and successful decongestion with acetazolamide in patients with acute decompensated heart failure (ADHF), suggests a study.
Natriuretic response to acetazolamide predicts decongestion in acute heart failure
22 May 2023Dupilumab cuts exacerbations, improves lung function in paediatric asthma patients with high eosinophils
In the post hoc analysis of data from the phase III LIBERTY ASTHMA VOYAGE study, the monoclonal antibody dupilumab reduced exacerbations and improved lung function in children aged between 6 and 11 years with moderate-to-severe asthma and baseline blood eosinophil count of ≥500 cells/μL.
Dupilumab cuts exacerbations, improves lung function in paediatric asthma patients with high eosinophils
22 May 2023Vitamin D supplementation exerts no effect on psoriasis severity in vitamin D-deficient individuals
Supplementation with vitamin D falls short of reducing psoriasis severity for individuals with 25-hydroxyvitamin D (25[OH]D) levels of <24 ng/mL, as reported in a study.