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Intravenous brivaracetam safe in paediatric epilepsy
Treatment with intravenous brivaracetam is well tolerated in children with epilepsy, with a safety profile consistent with that known of the oral formulation, according to the results of a phase II study. There has been no pharmacokinetic difference observed when administered as bolus or a 15-minute infusion.
Intravenous brivaracetam safe in paediatric epilepsy
21 Mar 2022Colchicine touted for prevention of gout flare-ups after COVID-19 vaccination
Gout patients have about sixfold greater odds of experiencing a flare in the first few months after COVID-19 vaccination, but colchicine appears to keep these gout attacks at bay, as shown in a study from China.
Colchicine touted for prevention of gout flare-ups after COVID-19 vaccination
18 Mar 2022Lower resilience tied to poorer medication adherence in glaucoma patients
The COVID-19 pandemic has worsened the adherence to ocular hypotensive medication among patients with primary open-angle glaucoma (POAG), according to a study. Such reduction is potentially driven by lower psychometric measures of resilience and more confrontational coping strategies.
Lower resilience tied to poorer medication adherence in glaucoma patients
18 Mar 2022Booster COVID-19 vacc cuts breakthrough infection risk, particularly in individuals with no immune dysfunction
Receipt of a booster dose of the COVID-19 vaccine reduces the risk of breakthrough COVID-19 infections* compared to full vaccination only, particularly among individuals without immunosuppressed/compromised conditions (ISC), according to a US study presented at CROI 2022.
Booster COVID-19 vacc cuts breakthrough infection risk, particularly in individuals with no immune dysfunction
17 Mar 2022DOAC use persists in NVAF patients with liver disease
A knowledge gap exists on the effects of direct oral anticoagulants (DOACs), but most nonvalvular atrial fibrillation (NVAF) patients with liver disease still begin treatment with these medications, particularly apixaban and rivaroxaban, a study has found.
DOAC use persists in NVAF patients with liver disease
17 Mar 2022Antihypertensive drugs up risk of psoriasis
Use of antihypertensive medications is associated with the incidence of psoriasis, reports a study. Beta-blockers, angiotensin-converting enzyme (ACE) inhibitors, calcium channel blockers (CCBs), and thiazide diuretics result in an increased risk of psoriasis.
Antihypertensive drugs up risk of psoriasis
17 Mar 2022Olaparib-abiraterone combo improves PFS in mCRPC
The combination of olaparib and abiraterone in the first-line setting improved radiographic progression-free survival (rPFS) in patients with metastatic castration-resistant prostate cancer (mCRPC), results of the phase III PROpel trial showed.