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Long-term methylphenidate use does not stunt growth in children with ADHD
Long-term treatment with methylphenidate does not increase risks of growth impairment and psychiatric or neurological adverse events (AEs) in children and adolescents with attention deficit hyperactivity disorder (ADHD), according to the international ADDUCE study co-led by the University of Hong Kong (HKU) and the University of Melbourne.
Long-term methylphenidate use does not stunt growth in children with ADHD
03 Apr 2023Tumour immune barrier determines immunotherapy efficacy in HCC
A tumour immune barrier (TIB) structure formed by the interaction of SPP1+ macrophages and cancer-associated fibroblasts (CAFs) appears to influence the efficacy of immunotherapy in patients with hepatocellular carcinoma (HCC), reveals a study.
Tumour immune barrier determines immunotherapy efficacy in HCC
01 Apr 2023Secukinumab yields sustained positive effects on molecular, histopathologic psoriasis markers
Treatment with secukinumab leads to sustained clinical response among patients with psoriasis, with clinical response being associated with rapid and persistent normalization of keratin 16 (K16) and inflammatory gene expression for most patients, according to data from the ObePso-S study.
Secukinumab yields sustained positive effects on molecular, histopathologic psoriasis markers
01 Apr 2023Long COVID: What are the risk and protective factors?
A population-based, multicentre study finds female gender, transportation-, logistics- or discipline-related occupation, living with domestic workers, smoking, poor or very poor self-perceived health status, ≥3 chronic diseases, chronic medication use, and critical severity of COVID-19 to be associated with severe long COVID, while prior receipt of ≥2 doses of COVID-19 vaccines serves as a protective factor.
Long COVID: What are the risk and protective factors?
01 Apr 2023Systemic antihypertensive medications exert diverse effects on glaucoma, IOP
The effects of systemic antihypertensive medications on glaucoma and intraocular pressure (IOP) appear to vary widely, according to the results of a systematic review and meta-analysis.
Systemic antihypertensive medications exert diverse effects on glaucoma, IOP
31 Mar 2023Certain ART combinations carry some risk of depression among women with HIV
Women with HIV who use antiretroviral therapy (ART) combinations such as tenofovir alafenamide (TAF) with a cobicistat-boosted integrase inhibitor (INSTI) or protease inhibitor (PI) appear to frequently show somatic depressive symptoms, according to data from the Women’s Interagency HIV Study (WIHS) presented at CROI 2023.