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PCSK9 inhibition tied to decreased psoriasis risk
Inhibition of the proprotein convertase subtilisin/kexin type 9 (PCSK9) pathway appears to be causally associated with a lower risk of psoriasis, regardless of the concentration levels of circulating low-density lipoprotein (LDL), according a two-sample Mendelian randomization study.
PCSK9 inhibition tied to decreased psoriasis risk
20 Mar 2023Telbivudine use during pregnancy safe, effective in HBsAG-positive mothers
Use of telbivudine (LdT) during the second trimester of pregnancy helps prevent mother-to-child transmission of hepatitis B virus, reveals a study. In addition, treatment with LdT during pregnancy is safe in the long term for both mothers and infants.
Telbivudine use during pregnancy safe, effective in HBsAG-positive mothers
20 Mar 2023Add-on amantadine of no help in hospitalized COVID-19 patients
The addition of amantadine to standard care falls short of improving the likelihood of recovery of patients hospitalized with COVID-19, according to a study.
Add-on amantadine of no help in hospitalized COVID-19 patients
20 Mar 2023SC trastuzumab cost-saving for HER2-positive breast cancer in Hong Kong
A cost minimization analysis based on a literature review and Hong Kong data suggests that using subcutaneous (CS) instead of intravenous (IV) trastuzumab for HER2-positive breast cancer (BC) patients can offer an annual saving of more than USD 8.3 million to the Hong Kong healthcare system.
SC trastuzumab cost-saving for HER2-positive breast cancer in Hong Kong
20 Mar 2023Frequent aspirin use protects against ovarian cancer even in women with genetic predisposition
Genetic susceptibility to ovarian cancer does not appear to modify the protective association between frequent aspirin use and the risk of developing the cancer, as shown in a study.
Frequent aspirin use protects against ovarian cancer even in women with genetic predisposition
19 Mar 2023How accurate is PPI test in GERD, chest pain diagnosis?
Use of the proton pump inhibitor (PPI) test showed acceptable sensitivity but poor specificity in diagnosing gastroesophageal reflux disease (GERD), a study has shown. The test, however, works better in GERD-related noncardiac chest pain (NCCP).